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Effect of prenatal stress and extremely low-frequency electromagnetic fields on anxiety-like behavior in female rats: With an emphasis on prefrontal cortex and hippocampus

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Hosseini E, Kianifard D · 2023

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Combined prenatal stress and ELF-EMF exposure produced more severe anxiety-like behavior and neurodegeneration than either stressor alone in female rats.

Plain English Summary

Summary written for general audiences

This study examined how prenatal stress and extremely low-frequency electromagnetic field (ELF-EMF) exposure, individually and combined, affected anxiety-like behavior and brain tissue in female rats. The researchers found that all treatment groups showed increased anxiety-like behavior, with the combined stress and EMF group showing the most severe effects, accompanied by neurodegeneration in the prefrontal cortex and hippocampus regions and altered expression of markers related to cell death and synaptic plasticity.

Why This Matters

The study investigates an interaction effect between two potential stressors rather than examining ELF-EMF effects in isolation. The findings are limited to animal models and prenatal exposure; direct translation to human health outcomes requires additional research.

Exposure Information

Specific exposure levels were not quantified in this study.

Cite This Study
Hosseini E, Kianifard D (2023). Effect of prenatal stress and extremely low-frequency electromagnetic fields on anxiety-like behavior in female rats: With an emphasis on prefrontal cortex and hippocampus.
Show BibTeX
@article{hosseini_e_kianifard_d_ce4405,
  author = {Hosseini E and Kianifard D},
  title = {Effect of prenatal stress and extremely low-frequency electromagnetic fields on anxiety-like behavior in female rats: With an emphasis on prefrontal cortex and hippocampus},
  year = {2023},
  doi = {10.1016/j.cgh.2023.06.001},
  
}
DOI: 10.1016/j.cgh.2023.06.001PubMed: 36942730

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