Micronucleus induction after whole-body microwave irradiation of rats.
Trosic I, Busljeta I, Kasuba V, Rozgaj R. · 2002
View Original AbstractMicronuclei in rat blood cells were significantly increased after eight radiofrequency microwave irradiation treatments compared with sham-exposed controls.
Plain English Summary
Researchers exposed adult male Wistar rats to continuous 2450 MHz radiofrequency microwave radiation for 2 hours a day, 7 days a week, for up to 30 days, at a power density of 5–10 mW/cm2. Peripheral blood smears were examined for micronuclei in polychromatic erythrocytes as an indicator of genotoxicity. Micronuclei per 1000 PCEs were significantly increased after eight irradiation treatments compared with sham-exposed controls. The researchers noted that an adaptive mechanism in both erythrocytopoiesis and genotoxicity likely appeared during the subchronic irradiation treatment.
Why This Matters
Significant differences in polychromatic erythrocyte counts were found on the 2nd, 8th, and 15th days between the control and treated groups. An increased influx of immature erythrocytes into circulation at the start of the experiment suggested that proliferation and maturation of nucleated erythropoietic cells were affected by the exposure. The researchers described these findings as indicators of radiation effects on bone-marrow erythropoiesis and their subsequent effects in circulating red cells. Animals were euthanized under ether anesthesia on the final irradiation day for each treated group.
Exposure Details
- Power Density
- 5 – 10 mW/cm²
- Source/Device
- 2450 MHz
- Exposure Duration
- 2 h a day, 7 days a week for up to 30 days
Exposure Context
This study used 5 – 10 mW/cm² for radio frequency:
- 500Mx above the Building Biology guideline of 0.1 μW/m²
- 8.3Mx above the BioInitiative Report recommendation of 0.0006 μW/cm²
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
To study the micronucleus induction after whole-body microwave irradiation of rats.
Adult male Wistar rats were exposed for 2 h a day, 7 days a week for up to 30 days to continuous 245...
The results for the time-course of PCEs indicated significant differences (P<0.05) for the 2nd, the ...
Show BibTeX
@article{i_2002_micronucleus_induction_after_wholebody_45,
author = {Trosic I and Busljeta I and Kasuba V and Rozgaj R.},
title = {Micronucleus induction after whole-body microwave irradiation of rats.},
year = {2002},
url = {http://www.sciencedirect.com/science/article/pii/S1383571802002140},
}