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Intermittent extremely low frequency electromagnetic fields cause DNA damage in a dose-dependent way

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Authors not listed · 2003

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Intermittent ELF-EMF exposure induced dose-dependent DNA single-strand and double-strand breaks in cultured human diploid fibroblasts at flux densities as low as 35 mu T, below ICNIRP guidelines.

Plain English Summary

Summary written for general audiences

Researchers exposed cultured human diploid fibroblasts to intermittent ELF electromagnetic fields. DNA damage was measured using alkaline and neutral comet assays. Exposure at 50 Hz sinusoidal, 1-24 h, 20-1,000 mu T, with a 5 min on/10 min off pattern induced dose-dependent and time-dependent DNA single-strand and double-strand breaks. Effects were observed at magnetic flux densities as low as 35 mu T, well below ICNIRP guidelines. The induced comet tail factors returned to normal within 9 h after exposure ended.

Why This Matters

The study's title states that intermittent extremely low frequency electromagnetic fields cause DNA damage in a dose-dependent way. The researchers concluded that the induced DNA damage is not based on thermal effects and raises concern about environmental threshold limit values for ELF exposure.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 50 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 50 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Unknown (2003). Intermittent extremely low frequency electromagnetic fields cause DNA damage in a dose-dependent way.
Show BibTeX
@article{intermittent_extremely_low_frequency_electromagnetic_fields_cause_dna_damage_in_a_dose_dependent_way_ce1497,
  author = {Unknown},
  title = {Intermittent extremely low frequency electromagnetic fields cause DNA damage in a dose-dependent way},
  year = {2003},
  doi = {10.1007/S00420-003-0446-5},
  
}

Quick Questions About This Study

The study used cultured human diploid fibroblasts.
The exposure was 50 Hz sinusoidal, 1-24 h duration, 20-1,000 mu T magnetic flux density, with a 5 min on/10 min off intermittent pattern.
Exposure induced dose-dependent and time-dependent DNA single-strand and double-strand breaks, with effects at magnetic flux densities as low as 35 mu T.
The induced comet tail factors returned to normal within 9 h after termination of exposure.
The researchers concluded that the induced DNA damage is not based on thermal effects and raises concern about environmental threshold limit values for ELF exposure.