High frequency electromagnetic fields (GSM signals) affect gene expression levels in tumor suppressor p53-deficient embryonic stem cells.
Czyz J, GuanK, ZengQ, NikolovaT, MeisterA, SchönbornF, SchudererJ, KusterN, WobusAM, · 2004
View Original AbstractCells lacking tumor suppressor genes show stress responses to cell phone radiation while normal cells don't, revealing genetic vulnerability.
Plain English Summary
Researchers exposed embryonic stem cells to cell phone radiation at 1.71 GHz (similar to GSM signals) and found that cells lacking the tumor suppressor gene p53 showed increased stress responses, including elevated heat shock proteins. Normal cells with functioning p53 showed no such effects. This suggests that genetic background determines how vulnerable cells are to radiofrequency radiation damage.
Why This Matters
This study reveals a critical vulnerability that the wireless industry rarely discusses: genetic variation determines who gets hurt by cell phone radiation. The researchers found that cells missing the p53 tumor suppressor gene responded to GSM signals with classic stress markers, while genetically normal cells appeared unaffected. What this means for you is significant. The p53 gene is often called the 'guardian of the genome' because it helps prevent cancer by detecting DNA damage. People with inherited p53 mutations (Li-Fraumeni syndrome affects roughly 1 in 20,000 people) or those whose p53 function is compromised by age, illness, or other environmental factors may be at heightened risk from wireless radiation. The reality is that safety standards assume everyone responds identically to EMF exposure, but this research demonstrates that genetic differences create vulnerable populations who may need extra protection.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 1.71 GHz, GSM 1800
Study Details
Effects of electromagnetic fields (EMF) simulating exposure to the Global System for Mobile Communications (GSM) signals were studied using pluripotent embryonic stem (ES) cells in vitro.
Wild-type ES cells and ES cells deficient for the tumor suppressor p53 were exposed to pulse modulat...
GSM-217 EMF induced a significant upregulation of mRNA levels of the heat shock protein, hsp70 of p5...
Our data indicate that the genetic background determines cellular responses to GSM modulated EMF
Show BibTeX
@article{j_2004_high_frequency_electromagnetic_fields_2008,
author = {Czyz J and GuanK and ZengQ and NikolovaT and MeisterA and SchönbornF and SchudererJ and KusterN and WobusAM and},
title = {High frequency electromagnetic fields (GSM signals) affect gene expression levels in tumor suppressor p53-deficient embryonic stem cells.},
year = {2004},
url = {https://pubmed.ncbi.nlm.nih.gov/15114639/},
}