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Cancer & Tumors345 citations

Handheld cellular telephone use and risk of brain cancer.

No Effects Found

Muscat JE, Malkin MG, Thompson S, Shore RE, Stellman SD, McRee D, Neugut AI, Wynder EL · 2000

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Our data suggest that use of handheld cellular telephones is not associated with risk of brain cancer.

Plain English Summary

Summary written for general audiences

Researchers conducted a case-control study in five US academic medical centers between 1994 and 1998 using a structured questionnaire, enrolling 469 adults with primary brain cancer and 422 matched controls. The median monthly hours of use were 2.5 for cases and 2.2 for controls, and the multivariate odds ratio for regular use was 0.85 (95% CI, 0.6-1.2). No association was observed according to duration of use (P = .54), and cerebral tumors occurred more often on the same side as phone use (26 vs 15 cases; P = .06) while temporal lobe tumors showed the opposite pattern (9 vs 5 cases; P = .33).

Exposure Information

Specific exposure levels were not quantified in this study. The study examined exposure from: Handheld cellular telephone

Study Details

To test the hypothesis that using handheld cellular telephones is related to the risk of primary brain cancer.

Case-control study conducted in 5 US academic medical centers between 1994 and 1998 using a structur...

The median monthly hours of use were 2.5 for cases and 2.2 for controls. Compared with patients who ...

Our data suggest that use of handheld cellular telephones is not associated with risk of brain cancer, but further studies are needed to account for longer induction periods, especially for slow-growing tumors with neuronal features.

Cite This Study
Muscat JE, Malkin MG, Thompson S, Shore RE, Stellman SD, McRee D, Neugut AI, Wynder EL (2000). Handheld cellular telephone use and risk of brain cancer. JAMA 284(23):3001-3007, 2000.
Show BibTeX
@article{je_2000_handheld_cellular_telephone_use_3261,
  author = {Muscat JE and Malkin MG and Thompson S and Shore RE and Stellman SD and McRee D and Neugut AI and Wynder EL},
  title = {Handheld cellular telephone use and risk of brain cancer.},
  year = {2000},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/11122586/},
}
PubMed: 11122586

Cited By (345 papers)

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Quick Questions About This Study

A case-control study was conducted in five US academic medical centers between 1994 and 1998 using a structured questionnaire.
The study included 469 adults with primary brain cancer and 422 matched controls without brain cancer.
The multivariate odds ratio for regular past or current use was 0.85 (95% CI, 0.6-1.2).
No association with brain cancer was observed according to duration of use (P = .54).
Cerebral tumors occurred more frequently on the same side as phone use (26 vs 15 cases; P = .06). Temporal lobe tumors were more often on the opposite side (9 vs 5 cases; P = .33).