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Thymidine decreases the DNA damage and apoptosis caused by tumor-treating fields in cancer cell lines
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Jeong H, Jo Y, Yoon M, Hong S · 2021
Thymidine prevented the DNA damage and apoptosis caused by tumor-treating fields in cancer cell lines.
Plain English Summary
Summary written for general audiences
Researchers exposed human glioblastoma cells and normal HaCaT cells to tumor-treating fields at 120 kHz and 1.2 V/cm after arresting the cell cycle with thymidine. In contrast, thymidine-treated cells did not show changes in colony formation, apoptosis, DNA damage, or gene expression.
Cite This Study
Jeong H, Jo Y, Yoon M, Hong S (2021). Thymidine decreases the DNA damage and apoptosis caused by tumor-treating fields in cancer cell lines.
Show BibTeX
@article{jeong_h_jo_y_yoon_m_hong_s_ce4059,
author = {Jeong H and Jo Y and Yoon M and Hong S},
title = {Thymidine decreases the DNA damage and apoptosis caused by tumor-treating fields in cancer cell lines},
year = {2021},
}Quick Questions About This Study
The fields were applied at 120 kHz and 1.2 V/cm.
Thymidine-treated cells showed no change in colony formation, apoptosis, DNA damage, or gene expression.
They suggested that combining tumor-treating fields with conventional treatments such as chemotherapy may enhance prognosis and decrease side effects.