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Cancer & Tumors

Repeated exposure of C3H/HeJ mice to ultra-wideband electromagnetic pulses: Lack of effects on mammary tumors.

No Effects Found

Jauchem JR, Frei MR, Dusch SJ, Lehnert HM, Kovatch RM · 2001

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Exposure to ultra-wideband electromagnetic pulses had no significant effect on mammary tumor development in C3H/HeJ mice.

Plain English Summary

Summary written for general audiences

Researchers exposed 100 C3H/HeJ mice to ultra-wideband electromagnetic pulses for 2 minutes once a week for 12 weeks, using 100 sham-control mice for comparison. There were no significant differences between groups in incidence of palpated mammary tumors, latency to tumor onset, rate of tumor growth, or animal survival. Histopathological evaluations also revealed no significant differences between the two groups in numbers of neoplasms across all tissues studied.

Why This Matters

The study investigated pulses composed of an ultra-wideband of frequencies, including those in the RF range. The exposure parameters included a peak electric field of 40 kV/m, a repetition rate of 1 kHz, and a pulse width of 1.9 ns. The researchers described C3H/HeJ mice as a well-established animal model of mammary cancer.

Exposure Details

Electric Field
40000 V/m
Source/Device
435 MHz or 2450 MHz
Exposure Duration
2 min once a week for 12 weeks

Exposure Context

This study used 40000 V/m for electric fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 435 MHz - 2.45 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 435 MHz - 2.45 GHzPower lines50/60 HzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Study Details

In this study, we investigated the effects of exposure to a unique type of electromagnetic energy: pulses composed of an ultra-wideband (UWB) of frequencies, including those in the RF range.

One hundred C3H/HeJ mice were exposed to UWB pulses (rise time 176 ps, fall time 3.5 ns, pulse width...

There were no significant differences between groups with respect to incidence of palpated mammary t...

Our major finding was the lack of effects of UWB-pulse exposure on promotion of mammary tumors in a well-established animal model of mammary cancer.

Cite This Study
Jauchem JR, Frei MR, Dusch SJ, Lehnert HM, Kovatch RM (2001). Repeated exposure of C3H/HeJ mice to ultra-wideband electromagnetic pulses: Lack of effects on mammary tumors. Radiat Res 155(2):369-377, 2001.
Show BibTeX
@article{jr_2001_repeated_exposure_of_c3hhej_3113,
  author = {Jauchem JR and Frei MR and Dusch SJ and Lehnert HM and Kovatch RM},
  title = {Repeated exposure of C3H/HeJ mice to ultra-wideband electromagnetic pulses: Lack of effects on mammary tumors.},
  year = {2001},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/11175673/},
}
PubMed: 11175673

Cited By (33 papers)

Quick Questions About This Study

The study examined pulses composed of an ultra-wideband of frequencies, including those in the RF range.
Each animal was exposed for 2 minutes once a week for 12 weeks, with a peak electric field of 40 kV/m and a repetition rate of 1 kHz.
The major finding was the lack of effects of UWB-pulse exposure on promotion of mammary tumors.
Histopathological evaluations covered lymphoreticular tissue, thymus, respiratory, digestive and urinary tracts, reproductive, mammary and endocrine systems, and skin, with no significant differences found.
One hundred mice were exposed to UWB pulses and one hundred mice were used as sham controls.