Pre and postnatal exposure to 900 MHz electromagnetic fields induce inflammation and oxidative stress, and alter renin- angiotensin system components differently in male and female offsprings
Kilic A, Ustunova S, Bulut H, Meral I · 2023
Prenatal and postnatal exposure to 900 MHz EMF increased oxidative stress, inflammation, and renin-angiotensin system components in the brain and kidney of both male and female rat offspring.
Plain English Summary
Researchers exposed male and female Wistar albino offspring to 900 MHz EMF for one hour per day during prenatal (23 days) and/or postnatal (40 days) periods and collected brain and kidney tissues at puberty. In all exposed groups, total oxidant status, IL-2, IL-6, and TNF-α rose while total antioxidant status fell in both sexes' brain and kidney tissues. Renin-angiotensin system components including angiotensinogen, renin, AT1, AT2, and MAS1-like receptor expression were also elevated in all exposed groups compared with controls.
Why This Matters
The authors noted that although male and female offspring showed some differences in marker levels, the overall effect of EMF exposure was an increase in oxidative stress, inflammation, and angiotensin system components in both brain and kidney. They concluded that 900 MHz EMF can activate the brain and kidney renin-angiotensin system, and this activation may be linked to inflammation and oxidative stress in both sexes.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{kilic_a_ustunova_s_bulut_h_meral_i_ce2457,
author = {Kilic A and Ustunova S and Bulut H and Meral I},
title = {Pre and postnatal exposure to 900 MHz electromagnetic fields induce inflammation and oxidative stress, and alter renin- angiotensin system components differently in male and female offsprings},
year = {2023},
doi = {10.1016/j.lfs.2023.121627},
}