Induction of micronuclei in human lymphocytes exposed in vitro to microwave radiation
Zotti-Martelli L, Peccatori M, Scarpato R, Migliore L · 2000
View Original AbstractAt 30 mW/cm2 and exposures of 30 and 60 minutes, both tested frequencies induced micronuclei in human lymphocytes in vitro.
Plain English Summary
Researchers exposed human peripheral blood lymphocytes in vitro to electromagnetic fields at two frequencies, 2.45 and 7.7 GHz, at power densities of 10, 20, and 30 mW/cm2 for 15, 30, and 60 minutes. At a power density of 30 mW/cm2 and after exposures of 30 and 60 minutes, both frequencies led to an induction of micronuclei compared to control cultures. The researchers concluded that microwaves are able to cause cytogenetic damage in human lymphocytes mainly for both high power density and long exposure time.
Why This Matters
The micronucleus assay was used as the measure of cytogenetic damage, described as a useful tool for detecting radiation exposure-induced cytogenetic damage. The lymphocytes were exposed in G0 across a range of conditions varying frequency, power density, and duration. The increased micronuclei were observed at 30 mW/cm2, and the study indicates that high power density and long exposure time were the key factors.
Exposure Details
- Power Density
- 10, 20 and 30 mW/cm²
- Source/Device
- 2.45 and 7.7 GHz
- Exposure Duration
- 15, 30 and 60 min
Exposure Context
This study used 10, 20 and 30 mW/cm² for radio frequency:
- 1,000Mx above the Building Biology guideline of 0.1 μW/m²
- 16.7Mx above the BioInitiative Report recommendation of 0.0006 μW/cm²
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
To study the induction of micronuclei in human lymphocytes exposed in vitro to microwave radiation.
The micronucleus (MN) assay which is proved to be a useful tool for the detection of radiation expos...
The results showed for both radiation frequencies an induction of micronuclei as compared to the con...
Our study would indicate that microwaves are able to cause cytogenetic damage in human lymphocytes mainly for both high power density and long exposure time.
Show BibTeX
@article{l_2000_induction_of_micronuclei_in_48,
author = {Zotti-Martelli L and Peccatori M and Scarpato R and Migliore L},
title = {Induction of micronuclei in human lymphocytes exposed in vitro to microwave radiation},
year = {2000},
url = {http://www.sciencedirect.com/science/article/pii/S1383571800001121},
}