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Influence of high-frequency electromagnetic fields on different modes of cell death and gene expression.

No Effects Found

Port M, Abend M, Romer B, Van Beuningen D. · 2003

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Even at 25 times occupational safety limits, pulsed electromagnetic fields showed no immediate cellular damage in this laboratory study.

Plain English Summary

Summary written for general audiences

German researchers exposed human leukemia cells to electromagnetic fields 25 times stronger than occupational safety limits to see if this would damage DNA, kill cells, or change gene activity. They found no significant effects on cell death, genetic damage, or the expression of over 1,100 genes. This suggests that even at very high exposure levels, these particular electromagnetic fields did not harm the cells in ways that could lead to cancer.

Study Details

The aim of this study was to examine whether biological effects such as different modes of cell death and gene expression modifications related to tumorgenesis are detectable above the threshold defined.

Human leukaemia cells (HL-60) grown in vitro were exposed to electromagnetic fields (EMF; t 1/2(r) a...

No significant change in apoptosis, micronucleation, abnormal cells and differential gene expression...

Exposure of HL-60 cells to EMFs 25 times higher than the ICNIRP reference levels for occupational exposure failed to induce any changes in apoptosis, micronucleation, abnormal morphologies and gene expression. Further experiments using EMFs above the conservatively defined reference level set by the ICNIRP may be desirable.

Cite This Study
Port M, Abend M, Romer B, Van Beuningen D. (2003). Influence of high-frequency electromagnetic fields on different modes of cell death and gene expression. Int J Radiat Biol. 79(9):701-708, 2003.
Show BibTeX
@article{m_2003_influence_of_highfrequency_electromagnetic_3308,
  author = {Port M and Abend M and Romer B and Van Beuningen D.},
  title = {Influence of high-frequency electromagnetic fields on different modes of cell death and gene expression.},
  year = {2003},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/14703943/},
}

Quick Questions About This Study

German researchers exposed human leukemia cells to electromagnetic fields 25 times stronger than occupational safety limits to see if this would damage DNA, kill cells, or change gene activity. They found no significant effects on cell death, genetic damage, or the expression of over 1,100 genes. This suggests that even at very high exposure levels, these particular electromagnetic fields did not harm the cells in ways that could lead to cancer.