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Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

DNA & Genetic Damage

DNA damage in rat brain cells after in vivo exposure to 2450 MHz electromagnetic radiation and various methods of euthanasia.

No Effects Found

Malyapa RS, Ahern EW, Bi C, Straube WL, LaRegina M, Pickard WF, Roti RotiJL, · 1998

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This study found no DNA damage in rat brain cells after 2-hour microwave exposure at levels exceeding cell phone limits.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to microwave radiation at 2450 MHz (the same frequency used in microwave ovens) for 2 hours to test whether it causes DNA breaks in brain cells. They found no DNA damage in either the brain's cortex or hippocampus regions, contradicting an earlier study that reported such damage. This suggests that short-term exposure to this type of microwave radiation at moderate levels may not harm brain cell DNA.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.45 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.45 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 2450 MHz Duration: 2 h

Study Details

The present study was done to confirm the reported observation that low-intensity acute exposure to 2450 MHz radiation causes DNA single-strand breaks (Lai and Singh, Bioelectromagnetics 16, 207-210, 1995).

Male Sprague-Dawley rats weighing approximately 250 g were irradiated with 2450 MHz continuous-wave ...

Irrespective of whether the rats were euthanized by CO2 asphyxia or decapitated by guillotine, no si...

Therefore, the guillotine method of euthanasia is the most appropriate in studies relating to DNA damage. Furthermore, we did not confirm the observation that DNA damage is produced in cells of the rat cerebral cortex or the hippocampus after a 2-h exposure to 2450 MHz CW microwaves or at 4 h after the exposure.

Cite This Study
Malyapa RS, Ahern EW, Bi C, Straube WL, LaRegina M, Pickard WF, Roti RotiJL, (1998). DNA damage in rat brain cells after in vivo exposure to 2450 MHz electromagnetic radiation and various methods of euthanasia. Radiat Res 149(6):637-645, 1998.
Show BibTeX
@article{rs_1998_dna_damage_in_rat_2920,
  author = {Malyapa RS and Ahern EW and Bi C and Straube WL and LaRegina M and Pickard WF and Roti RotiJL and},
  title = {DNA damage in rat brain cells after in vivo exposure to 2450 MHz electromagnetic radiation and various methods of euthanasia.},
  year = {1998},
  
  url = {https://meridian.allenpress.com/radiation-research/article-abstract/149/6/637/40821/DNA-Damage-in-Rat-Brain-Cells-after-In-Vivo},
}

Quick Questions About This Study

No, a 1998 study found that 2-hour exposure to 2450 MHz microwave radiation (the same frequency as microwave ovens) caused no DNA damage in rat brain cells. Researchers examined both the cortex and hippocampus regions and found no significant DNA breaks compared to unexposed rats.
CO2 asphyxiation caused more intrinsic DNA damage and experimental variation compared to guillotine euthanasia in the 1998 study. The researchers concluded that guillotine method is more appropriate for DNA damage studies because CO2 creates background damage that can interfere with results.
Research from 1998 shows that 2-hour exposure to 2450 MHz radiation (microwave oven frequency) did not damage DNA in rat brain cells. The study examined both immediate effects and damage 4 hours after exposure, finding no significant harm to brain tissue.
No, this 1998 research contradicted an earlier study that reported DNA damage from microwave radiation. The researchers could not confirm that 2450 MHz exposure causes DNA breaks in rat brain cortex or hippocampus cells, suggesting the previous findings may have been incorrect.
Researchers examined DNA damage in two specific brain regions: the cerebral cortex and hippocampus of rats exposed to 2450 MHz radiation. Both areas showed no significant DNA damage compared to unexposed control animals, indicating these critical brain regions remain unharmed by moderate microwave exposure.