Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
Hsp70 expression and free radical release after exposure to non-thermal radio-frequency electromagnetic fields and ultrafine particles in human Mono Mac 6 cells.
Simko M, Hartwig C, Lantow M, Lupke M, Mattsson MO, Rahman Q, Rollwitz J · 2006
View Original AbstractRF radiation at cell phone levels failed to trigger stress responses in immune cells, unlike air pollution particles which caused significant effects.
Plain English Summary
German researchers exposed human immune cells (monocytes) to radiofrequency radiation at 2 W/kg SAR - similar to cell phone levels - while also testing exposure to ultrafine air pollution particles. They measured two key stress indicators: free radical production and heat shock proteins. While the air pollution particles triggered significant stress responses, the RF radiation produced no measurable effects on either stress marker, even when combined with the particles.
Study Details
The contemporary urban environment has become increasingly complex in its composition, leading to discussions regarding possible novel health effects. Two factors that recently have received considerable attention are ultrafine particles (UFP; <0.1 microm) produced by combustion processes and emissions from wireless communication devices like mobile phones that emit in the radio-frequency (RF) part of the spectrum. Several studies have shown biological effects of both these exposures in various cell systems. Here we investigate if exposure to UFP (12-14 nm, 100 microg/ml) and RF-electromagnetic fields (EMF; 2 W/kg specific absorption rate (SAR); continuous wave (CW) or modulated (217Hz or GSM-nonDTX)), alone or in combination influences levels of the superoxide radical anion or the stress protein heat-shock protein (Hsp70) in the human monocyte cell line Mono Mac 6. Heat treatment (42-43 degrees C, 1h) was used as positive control for both stress reaction and for heat development in the RF exposure setup.
Our results clearly show that Mono Mac 6 cells are capable to internalise UFP, and that this phagocy...
Therefore, we conclude that in the investigated Mono Mac 6 cells, RF exposure alone or in combination with UFP cannot influence stress-related responses.
Show BibTeX
@article{m_2006_hsp70_expression_and_free_3402,
author = {Simko M and Hartwig C and Lantow M and Lupke M and Mattsson MO and Rahman Q and Rollwitz J},
title = {Hsp70 expression and free radical release after exposure to non-thermal radio-frequency electromagnetic fields and ultrafine particles in human Mono Mac 6 cells.},
year = {2006},
url = {https://pubmed.ncbi.nlm.nih.gov/16153791/},
}