Maternal mobile phone exposure adversely affects the electrophysiological properties of Purkinje neurons in rat offspring
Haghani M, Shabani M, Moazzami K · 2013
View Original AbstractPrenatal EMF exposure resulted in altered electrophysiological properties of Purkinje neurons in rat offspring, though no behavioral abnormalities were detected.
Plain English Summary
Researchers exposed pregnant Wistar rats to 900-MHz pulse-EMF irradiation for 6 hours per day throughout gestation, then evaluated ten offspring per group. Behavioral tests did not reveal any abnormalities in the exposed offspring. Whole-cell patch clamp recordings revealed decreased neuronal excitability of Purkinje cells, with changes in afterhyperpolarization amplitude, spike frequency, half width, and first spike latency.
Why This Matters
The study aimed to examine the possible effects of prenatal EMF exposure on the cerebellum of offspring Wistar rats. Behavioral tests used included the Accelerated Rotarod, Hanging, and Open field tests, which are designed to detect cerebellum-related dysfunction. Although electrical signaling in Purkinje cells was altered, the researchers noted these changes may not have been severe enough to affect cerebellum-dependent tasks.
Exposure Details
- SAR
- 0.5 and 0.9 W/kg
- Source/Device
- 900-MHz pulse-EMF
- Exposure Duration
- 6 h per day during gestation
Exposure Context
This study used 0.5 and 0.9 W/kg for SAR (device absorption):
- 1.3x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
In the present study, we aimed to elucidate the possible effects of prenatal EMF exposure on the cerebellum of offspring Wistar rats.
Rats in the EMF group were exposed to 900-MHz pulse-EMF irradiation for 6 h per day during all gesta...
The results of the present study failed to show any behavioral abnormalities in rats exposed to chro...
In conclusion, the results of the present study show that prenatal EMF exposure results in altered electrophysiological properties of Purkinje neurons. However, these changes may not be severe enough to alter the cerebellum-dependent functional tasks.
Show BibTeX
@article{m_2013_maternal_mobile_phone_exposure_104,
author = {Haghani M and Shabani M and Moazzami K},
title = {Maternal mobile phone exposure adversely affects the electrophysiological properties of Purkinje neurons in rat offspring},
year = {2013},
url = {https://www.sciencedirect.com/science/article/abs/pii/S030645221300643X},
}