Terahertz radiation affects the dynamics of neurons by decreasing membrane area ratio
Ma S, Li S, Wang H, Li Y, Lu C, Li X · 2025
Terahertz radiation can modulate neuronal morphology and firing patterns through changes in membrane structure, potentially offering a novel approach for neuromodulation in treating neuronal degenerative diseases.
Plain English Summary
This study investigated how terahertz radiation affects neuronal morphology and function in a technical model system. The researchers found that terahertz radiation decreased the membrane area ratio of neuronal cytosol to protrusions, which correlated with changes in neuronal firing patterns, including reduced inter-cluster discharge frequency and action potential amplitude, while increasing intra-cluster discharge and postsynaptic current peaks.
Why This Matters
This appears to be a computational or in vitro modeling study examining terahertz-induced effects on neuronal properties rather than in vivo animal research. The findings propose a mechanistic link between morphological changes and electrophysiological alterations, though the translation to therapeutic applications would require further validation.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{ma_s_li_s_wang_h_li_y_lu_c_li_x_ce3359,
author = {Ma S and Li S and Wang H and Li Y and Lu C and Li X},
title = {Terahertz radiation affects the dynamics of neurons by decreasing membrane area ratio},
year = {2025},
doi = {10.1038/s41586-025-09422-z},
}