Autophagy is modulated in human neuroblastoma cells through direct exposition to low frequency electromagnetic fields
Bioeffects Seen
Marchesi N, Osera C, Fassina L, Amadio M, Angeletti F, Morini M, Magenes G, Venturini L, Biggiogera M, Ricevuti G, Govoni S, Caorsi S, Pascale A, Comincini S ·2014
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Low frequency electromagnetic field exposure modulates autophagy in human neuroblastoma cells, suggesting EMF may influence cellular stress response mechanisms.
Plain English Summary
Summary written for general audiences
This study examined how low frequency electromagnetic fields affect autophagy (cellular self-cleaning processes) in human neuroblastoma cells through direct exposure. The research investigated modulation of autophagy pathways as a cellular response to electromagnetic field exposure.
Why This Matters
Autophagy is a cellular maintenance process implicated in both cell survival and cell death pathways, making it relevant to understanding potential biological effects of environmental stressors. Neuroblastoma cells are commonly used as an in vitro model for studying cellular responses to various exposures, though results from cell culture studies require further validation in more complex biological systems.
Exposure Information
Specific exposure levels were not quantified in this study.
Cite This Study
Marchesi N, Osera C, Fassina L, Amadio M, Angeletti F, Morini M, Magenes G, Venturini L, Biggiogera M, Ricevuti G, Govoni S, Caorsi S, Pascale A, Comincini S (2014). Autophagy is modulated in human neuroblastoma cells through direct exposition to low frequency electromagnetic fields.
Show BibTeX
@article{marchesi_n_osera_c_fassina_l_amadio_m_angeletti_f_morini_m_magenes_g_venturini_l_biggiogera_m_ricevuti_g_govoni_s_caorsi_s_pascale_a_comincini_s_ce4487,
author = {Marchesi N and Osera C and Fassina L and Amadio M and Angeletti F and Morini M and Magenes G and Venturini L and Biggiogera M and Ricevuti G and Govoni S and Caorsi S and Pascale A and Comincini S},
title = {Autophagy is modulated in human neuroblastoma cells through direct exposition to low frequency electromagnetic fields},
year = {2014},
doi = {10.1016/j.bj.2024.100824},
}
EMF exposure interferes with natural biological processes including photoentrainment, ion cyclotron resonance, and radical-pair formation. These mechanisms affect melatonin and cortisol production, disrupting the body's natural sleep-wake cycle and hormonal balance.
Yes, the combination of artificial lighting, irregular schedules, and EMF exposure creates multiple disruptions to circadian rhythms. This compound effect can lead to increased inflammation and higher risk of chronic diseases.
Intracellular water exists in a coherent, ordered phase that's sensitive to infrared light and electromagnetic fields. This structured water may respond to both solar variations and man-made EMF, potentially affecting cellular function.
Yes, seasonal solar changes and sunspot cycles can influence biological rhythms through similar mechanisms as artificial EMF exposure. Both natural and man-made electromagnetic fields can disrupt melatonin and cortisol regulation.
Research indicates that circadian disruption from EMF exposure can produce inflammation and initiate or aggravate chronic diseases by interfering with the body's natural hormonal cycles and cellular repair processes.
