6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.
Shield Your Body

Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

DNA & Genetic Damage

Does radio frequency radiation induce micronuclei frequency in exfoliated bladder cells of diabetic rats?

No Effects Found

Gurbuz N, Sirav B, Kuzay D, Ozer C, Seyhan N. · 2015

View Original Abstract
Share:

Cell phone radiation at 0.24 W/kg SAR showed no genetic damage in rat bladder cells, even in diabetic animals.

Plain English Summary

Summary written for general audiences

Researchers exposed diabetic rats to cell phone radiation (2100 MHz) to see if it caused genetic damage in bladder cells by looking for micronuclei - small fragments of broken DNA that indicate cellular damage. They found no increase in genetic damage in either healthy or diabetic rats exposed to the radiation compared to unexposed animals. The study suggests that this level of RF radiation may not cause DNA damage in bladder cells, even in animals with diabetes who might be more vulnerable.

Why This Matters

This study examined genetic damage at the cellular level using a well-established biomarker - micronuclei formation in bladder cells. The researchers specifically chose diabetic rats because diabetes can make organisms more susceptible to environmental stressors, potentially revealing effects that might be missed in healthy subjects. The exposure level (0.24 W/kg SAR) falls well below current safety limits and represents relatively low-level exposure. However, the study's small sample size (only 6 animals per group) and unspecified exposure duration limit the strength of its conclusions. While this research found no genotoxic effects, it represents just one data point in a much larger body of research on RF radiation and DNA damage. The science on EMF-induced genetic damage remains mixed, with some studies showing effects and others, like this one, showing none.

Exposure Details

SAR
0.24 W/kg
Electric Field
17.5 V/m
Source/Device
2100 MHz

Exposure Context

This study used 17.5 V/m for electric fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.24 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 7 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.10 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.10 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

The purpose of the present study was to evaluate the relationship of micronucleui (MN) frequency and RF radiation in exfoliated bladder cells of non-diabetic and diabetic rats.

Three groups were used in the experiment: Group I (n=6): diabetic group without RF exposure; Group I...

Results showed that there was no statistically important differences between non-RF exposed diabetes...

This study suggested no possible genotoxic effects of RF radiation among human beings especially with chronic disorders, such as diabetes.

Cite This Study
Gurbuz N, Sirav B, Kuzay D, Ozer C, Seyhan N. (2015). Does radio frequency radiation induce micronuclei frequency in exfoliated bladder cells of diabetic rats? Endocr Regul. 49(3):126-130, 2015.
Show BibTeX
@article{n_2015_does_radio_frequency_radiation_3054,
  author = {Gurbuz N and Sirav B and Kuzay D and Ozer C and Seyhan N.},
  title = {Does radio frequency radiation induce micronuclei frequency in exfoliated bladder cells of diabetic rats?},
  year = {2015},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/26238494/},
}
PubMed: 26238494

Cited By (4 papers)

Quick Questions About This Study

No, a 2015 study found that 2100 MHz cell phone radiation did not cause genetic damage in bladder cells of diabetic rats. Researchers measured micronuclei formation as an indicator of DNA damage and found no statistically significant increases in either diabetic or healthy rats exposed to the radiation.
Research using 2100 MHz radiation on rat bladder cells found no increase in micronuclei formation. The study specifically examined exfoliated bladder cells from both healthy and diabetic rats, showing no statistically significant differences in genetic damage markers between exposed and unexposed groups.
A 2015 study suggests diabetic individuals may not be at increased risk for genetic damage from 2100 MHz cell phone radiation. The research found no difference in DNA damage markers between diabetic and healthy rats exposed to this frequency, indicating diabetes doesn't increase vulnerability.
Researchers used 2100 MHz radiofrequency radiation to test for genetic damage in rat bladder cells. This frequency corresponds to common cell phone operating frequencies. The study examined both diabetic and healthy rats to assess potential DNA damage through micronuclei analysis in exfoliated bladder cells.
Based on research with diabetic rats exposed to 2100 MHz radiation, chronic illness may not increase genetic damage risk from cell phone frequencies. The study found no significant differences in DNA damage markers between healthy and diabetic animals, suggesting chronic conditions don't heighten vulnerability.