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The genotoxic effect of radiofrequency waves on mouse brain.

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Cogulu O. · 2012

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Mouse brain cell cultures exposed to radiofrequency waves showed an 11-fold increase in micronuclei and a 7-fold decrease in STAT3 expression.

Plain English Summary

Summary written for general audiences

Researchers exposed mouse brain cell cultures to radiofrequency waves to evaluate genotoxic effects. The cultures were exposed to 10.715 GHz signals at a specific absorption rate of 0.725 W/kg for 6 hours over 3 days at 25°C. The study measured changes in the micronucleus assay and in the expression of 11 proapoptotic and antiapoptotic genes. The micronuclei rate increased 11-fold and STAT3 expression decreased 7-fold in the exposed cell cultures.

Exposure Details

SAR
0.725 W/kg
Source/Device
Signal Generator
Exposure Duration
6h in 3d

Exposure Context

This study used 0.725 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.725 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 2 times higher than this level

Study Details

Concerns about the health effects of radiofrequency (RF) waves have been raised because of the gradual increase in usage of cell phones, and there are scientific questions and debates about the safety of those instruments in daily life. The aim of this study is to evaluate the genotoxic effects of RF waves in an experimental brain cell culture model.

Brain cell cultures of the mice were exposed to 10.715 GHz with specific absorbtion rate (SAR) 0.725...

It was found that MNi rate increased 11-fold and STAT3 expression decreased 7-fold in the cell cultu...

Cell phones which spread RF may damage DNA and change gene expression in brain cells.

Cite This Study
Cogulu O. (2012). The genotoxic effect of radiofrequency waves on mouse brain. Neurooncol 106:53-58, 2012.
Show BibTeX
@article{o._2012_the_genotoxic_effect_of_3,
  author = {Cogulu O.},
  title = {The genotoxic effect of radiofrequency waves on mouse brain.},
  year = {2012},
  doi = {10.1007/s11060-011-0644-z},
  url = {http://link.springer.com/article/10.1007/s11060-011-0644-z},
}
DOI: 10.1007/s11060-011-0644-z

Cited By (42 papers)

Quick Questions About This Study

The study used brain cell cultures taken from mice, examined in an experimental cell culture model.
The cells were exposed to 10.715 GHz signals at a SAR of 0.725 W/kg for 6 hours over 3 days at 25°C.
The micronuclei rate increased 11-fold in the cell cultures that were exposed to RF.
The researchers suggested that RF waves may damage DNA and change gene expression in brain cells.
The study was motivated by concerns about health effects of RF waves raised by the gradual increase in usage of cell phones.