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Exposure of nerve growth factor-treated PC12 rat pheochromocytoma cells to a modulated radiofrequency field at 836.55 MHz: effects on c-jun and c-fos expression.

No Effects Found

Ivaschuk OI, Jones RA, Ishida-Jones T, Haggren W, Adey WR, Phillips JL · 1997

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Cell phone radiation at 9 mW/cm² reduced nerve cell gene activity by 38%, showing biological effects at exposure levels comparable to device use.

Plain English Summary

Summary written for general audiences

Researchers exposed rat nerve cells to cell phone radiation at 836.55 MHz (the frequency used by early digital cell phones) to see if it would affect the activity of genes called c-fos and c-jun, which help control cell growth and responses to stress. They found mostly no effects, except for a 38% decrease in c-jun gene activity at the highest exposure level of 9 mW/cm². This suggests that cell phone radiation may have subtle effects on nerve cell gene expression, but only at relatively high exposure levels.

Study Details

The aim of this study is to investigate Exposure of nerve growth factor-treated PC12 rat pheochromocytoma cells to a modulated radiofrequency field at 836.55 MHz: effects on c-jun and c-fos expression.

Rat PC12 pheochromocytoma cells have been treated with nerve growth factor and then exposed to ather...

No change in c-fos transcript levels were detected after 20 min exposure at each field intensity (20...

Cite This Study
Ivaschuk OI, Jones RA, Ishida-Jones T, Haggren W, Adey WR, Phillips JL (1997). Exposure of nerve growth factor-treated PC12 rat pheochromocytoma cells to a modulated radiofrequency field at 836.55 MHz: effects on c-jun and c-fos expression. Bioelectromagnetics 18(3):223-229, 1997.
Show BibTeX
@article{oi_1997_exposure_of_nerve_growth_3108,
  author = {Ivaschuk OI and Jones RA and Ishida-Jones T and Haggren W and Adey WR and Phillips JL},
  title = {Exposure of nerve growth factor-treated PC12 rat pheochromocytoma cells to a modulated radiofrequency field at 836.55 MHz: effects on c-jun and c-fos expression.},
  year = {1997},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/9096840/},
}

Quick Questions About This Study

Researchers exposed rat nerve cells to cell phone radiation at 836.55 MHz (the frequency used by early digital cell phones) to see if it would affect the activity of genes called c-fos and c-jun, which help control cell growth and responses to stress. They found mostly no effects, except for a 38% decrease in c-jun gene activity at the highest exposure level of 9 mW/cm². This suggests that cell phone radiation may have subtle effects on nerve cell gene expression, but only at relatively high exposure levels.