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Evaluation of HSP70 Expression and DNA Damage in Cells of a Human Trophoblast Cell Line Exposed to 1.8 GHz Amplitude-Modulated Radiofrequency Fields.

No Effects Found

Valbonesi P, Franzellitti S, Piano A, Contin A, Biondi C, Fabbri E. · 2008

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One hour of GSM cell phone radiation at twice safety limits caused no DNA damage in placental cells, but longer exposures remain unstudied.

Plain English Summary

Summary written for general audiences

Researchers exposed human placental cells to cell phone radiation (1.8 GHz GSM signals) for one hour at levels twice the current safety limit to see if it would trigger cellular stress responses or DNA damage. The radiation exposure produced no detectable effects on stress proteins or DNA integrity, unlike positive control treatments that did cause measurable damage. This suggests that short-term exposure to this type of cell phone radiation may not immediately harm these particular cells.

Study Details

The aim of this study was to determine whether high-frequency electromagnetic fields (EMFs) could induce cellular effects.

The human trophoblast cell line HTR-8/SVneo was used as a model to evaluate the expression of protei...

HSP70 expression was significantly enhanced by heat, which was applied as the prototypical stimulus....

Overall, no evidence was found that a 1-h exposure to GSM-217 Hz induced a HSP70-mediated stress response or primary DNA damage in HTR-8/SVneo cells. Nevertheless, further investigations on trophoblast cell responses after exposure to GSM signals of different types and durations are needed.

Cite This Study
Valbonesi P, Franzellitti S, Piano A, Contin A, Biondi C, Fabbri E. (2008). Evaluation of HSP70 Expression and DNA Damage in Cells of a Human Trophoblast Cell Line Exposed to 1.8 GHz Amplitude-Modulated Radiofrequency Fields. Radiat Res. 169(3):270-279, 2008.
Show BibTeX
@article{p_2008_evaluation_of_hsp70_expression_3461,
  author = {Valbonesi P and Franzellitti S and Piano A and Contin A and Biondi C and Fabbri E.},
  title = {Evaluation of HSP70 Expression and DNA Damage in Cells of a Human Trophoblast Cell Line Exposed to 1.8 GHz Amplitude-Modulated Radiofrequency Fields.},
  year = {2008},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/18302482/},
}

Quick Questions About This Study

Researchers exposed human placental cells to cell phone radiation (1.8 GHz GSM signals) for one hour at levels twice the current safety limit to see if it would trigger cellular stress responses or DNA damage. The radiation exposure produced no detectable effects on stress proteins or DNA integrity, unlike positive control treatments that did cause measurable damage. This suggests that short-term exposure to this type of cell phone radiation may not immediately harm these particular cells.