Influence of electromagnetic field (1800 MHz) on lipid peroxidation in brain, blood, liver and kidney in rats
Bodera P, Stankiewicz W, Antkowiak B, Paluch M, Kieliszek J, Sobiech J, Niemcewicz M · 2015
View Original AbstractRepeated 1800 MHz EMF exposure combined with tramadol slightly elevated lipid peroxidation markers in the brain, blood, and kidneys of rats, but overall results did not differ significantly.
Plain English Summary
Researchers measured malondialdehyde (MDA), a marker of lipid peroxidation, in the blood, liver, kidneys, and brain of Wistar rats that were healthy or had inflammation, and exposed them repeatedly to 1800 MHz EMF. The exposure was repeated five times for 15 minutes and was studied both alone and combined with the opioid painkiller tramadol. MDA levels were slightly elevated in the blood, kidney, and brain of healthy rats in EMF-exposed groups treated with tramadol, while MDA in the liver remained at the same level across all groups. Overall, results for healthy rats and animals with inflammation did not differ significantly.
Why This Matters
The study divided animals into groups including a control group (CON), an exposed group (EMF), a tramadol-treated group (TRAM), and a group both exposed and treated with tramadol (TRAM/EMF). Lipid peroxidation was assessed by measuring MDA, which the researchers described as the end-product of the lipid peroxidation process. In the inflammation group, slightly increased MDA values were observed in the control and EMF-exposed groups, but kidney MDA values stayed at the same level in the control, exposed, and non-exposed tramadol-treated animals. The researchers concluded that EMF combined with tramadol slightly enhanced lipid peroxidation in brain, blood, and kidneys, but the overall difference between healthy and inflamed animals was not significant.
Exposure Details
- Magnetic Field
- 0.000062 mT
- SAR
- 0.024 to 0.028 W/kg
- Electric Field
- 20 V/m
- Source/Device
- 1,800 MHz
- Exposure Duration
- 15 min for 5 times/day
Exposure Context
This study used 20 V/m for electric fields:
- 66.7x above the Building Biology guideline of 0.3 V/m
This study used 0.000062 mT for magnetic fields:
- 3.1x above the Building Biology guideline of 0.2 mG
- 0.6x above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
The aim of this study is the evaluation of the influence of repeated (5 times for 15 min) exposure to electromagnetic field (EMF) of 1800 MHz frequency on tissue lipid peroxidation (LPO) both in normal and inflammatory state, combined with analgesic treatment.
The concentration of malondialdehyde (MDA) as the end-product of the lipid peroxidation (LPO) was es...
The slightly elevated levels of the MDA in blood, kidney, and brain were observed among healthy rats...
The electromagnetic field exposure (EMF), applied in the repeated manner together with opioid drug tramadol (TRAM), slightly enhanced lipid peroxidation level in brain, blood, and kidneys.
Show BibTeX
@article{p_2015_influence_of_electromagnetic_field_71,
author = {Bodera P and Stankiewicz W and Antkowiak B and Paluch M and Kieliszek J and Sobiech J and Niemcewicz M},
title = {Influence of electromagnetic field (1800 MHz) on lipid peroxidation in brain, blood, liver and kidney in rats},
year = {2015},
url = {https://pubmed.ncbi.nlm.nih.gov/26216313/},
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