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Amino acid concentrations in hypothalamic and caudate nuclei during microwave-induced thermal stress: analysis by microdialysis.

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Mason PA, Escarciga R, Doyle JM, Romano WF, Berger RE, Donnellan JP · 1997

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Microwave radiation at high power levels altered brain chemistry in multiple regions, showing thermal RF exposure can disrupt normal neurological function.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to high-power 5.02 GHz microwave radiation, heating their brains to dangerous temperatures. This thermal stress significantly increased three amino acid concentrations in critical brain regions including the hypothalamus. The findings suggest microwave heating disrupts normal brain chemistry beyond temperature-control areas.

Why This Matters

This study reveals how microwave radiation can alter brain chemistry through thermal effects, demonstrating measurable biochemical changes in response to heating. The SAR levels used (29-40 W/kg) are extraordinarily high compared to everyday exposures - your cell phone typically produces around 1.6 W/kg or less. However, the research is significant because it shows that radiofrequency radiation can produce detectable neurochemical changes when sufficient heating occurs. The fact that amino acid concentrations changed in multiple brain regions, not just temperature-control centers, suggests thermal stress from RF radiation has broader neurological implications than previously understood. What this means for you is that while normal device usage operates at much lower power levels, this research adds to our understanding of how RF energy interacts with brain tissue at the biochemical level.

Exposure Details

SAR
29, 40 W/kg
Source/Device
5.02 GHz
Exposure Duration
40 min

Exposure Context

This study used 29, 40 W/kg for SAR (device absorption):

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 29, 40 W/kgExtreme Concern0.1 W/kgFCC Limit1.6 W/kgEffects observed in the Extreme Concern range (Building Biology)FCC limit is 0x higher than this exposure level

Study Details

To investigate the effects of thermal stress produced by exposure to 5.02 GHz irradiation on amino acid concentration in the hypothalamus and caudate nucleus of rats.

Extracellular amino acid concentrations in the hypothalamus (Hyp) and caudate nucleus (CN) were meas...

In the Hyp and CN, the concentrations of aspartic acid, serine, and glycine increased significantly ...

Cite This Study
Mason PA, Escarciga R, Doyle JM, Romano WF, Berger RE, Donnellan JP (1997). Amino acid concentrations in hypothalamic and caudate nuclei during microwave-induced thermal stress: analysis by microdialysis. Bioelectromagnetics 18(3):277-283, 1997.
Show BibTeX
@article{pa_1997_amino_acid_concentrations_in_1191,
  author = {Mason PA and Escarciga R and Doyle JM and Romano WF and Berger RE and Donnellan JP},
  title = {Amino acid concentrations in hypothalamic and caudate nuclei during microwave-induced thermal stress: analysis by microdialysis.},
  year = {1997},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/9096847/},
}

Quick Questions About This Study

Researchers exposed rats to high-power 5.02 GHz microwave radiation, heating their brains to dangerous temperatures. This thermal stress significantly increased three amino acid concentrations in critical brain regions including the hypothalamus. The findings suggest microwave heating disrupts normal brain chemistry beyond temperature-control areas.