Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
Lack of effect of 94 GHz radio frequency radiation exposure in an animal model of skin carcinogenesis.
Mason PA, Walters TJ, DiGiovanni J, Beason CW, Jauchem JR, Dick EJ Jr, Mahajan K, Dusch SJ, Shields BA, Merritt JH, Murphy MR, Ryan KL · 2001
View Original AbstractEven at exposure levels 1000 times higher than safety limits, 94 GHz radiation showed no cancer-promoting effects in mice.
Plain English Summary
Researchers exposed mice to 94 GHz millimeter wave radiation (the same frequency range used in some 5G networks) to see if it would promote skin cancer development. Even at very high power levels - 1000 times stronger than typical exposure limits - the radiation showed no effect on tumor formation or growth. This suggests that millimeter wave radiation at these frequencies does not act as a cancer promoter in skin tissue.
Why This Matters
This study provides important reassurance about millimeter wave frequencies, particularly relevant given their use in 5G networks and military applications. The researchers used exposure levels of 333-1000 milliwatts per square centimeter, which are thousands of times higher than what you'd encounter from typical wireless devices. The science demonstrates that even these extreme exposures failed to promote cancer development in a well-established animal model specifically designed to detect cancer-promoting effects. What this means for you is that the millimeter wave frequencies used in some 5G applications appear unlikely to promote skin cancer, even at exposure levels far exceeding real-world scenarios. However, this single study shouldn't be viewed in isolation - the reality is that research on millimeter wave health effects remains limited, and more studies across different biological endpoints are needed for a complete picture.
Exposure Details
- Power Density
- 333 - 1000 mW/cm²
- Source/Device
- 94 GHz
- Exposure Duration
- 2 exposures/week for 12 weeks
Exposure Context
This study used 333 - 1000 mW/cm² for radio frequency:
- 33,300Mx above the Building Biology guideline of 0.1 μW/m²
- 555Mx above the BioInitiative Report recommendation of 0.0006 μW/cm²
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
In this study we investigated whether a single (1.0 W/cm(2) for 10 s) or repeated (2 exposures/week for 12 weeks, 333 mW/cm(2) for 10 s) exposure to 94 GHz RFR serves as a promoter or co-promoter in the 7,12-dimethylbenz[a]anthracene (DMBA)-induced SENCAR mouse model of skin carcinogenesis.
Neither paradigm of MMW exposure significantly affected papilloma development, as evidenced by a lac...
Therefore, we conclude that exposure to 94 GHz RFR under these conditions does not promote or co-promote papilloma development in this animal model of skin carcinogenesis.
Show BibTeX
@article{pa_2001_lack_of_effect_of_3233,
author = {Mason PA and Walters TJ and DiGiovanni J and Beason CW and Jauchem JR and Dick EJ Jr and Mahajan K and Dusch SJ and Shields BA and Merritt JH and Murphy MR and Ryan KL},
title = {Lack of effect of 94 GHz radio frequency radiation exposure in an animal model of skin carcinogenesis.},
year = {2001},
url = {https://pubmed.ncbi.nlm.nih.gov/11577012/},
}Cited By (39 papers)
- Radio frequency electromagnetic fields: Cancer, mutagenesis, and genotoxicityInfluential
L. Heynick et al. (2003) - 80 citations
- Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic miceInfluential
P. Heikkinen et al. (2003) - 53 citations
- Effects of 100 GHz radiation on alkaline phosphatase activity and antigen–antibody interactionInfluential
A. Homenko et al. (2009) - 35 citations
- Epidemiology of Health Effects of Radiofrequency Exposure
A. Ahlbom et al. (2004) - 374 citations
- Impact of radio frequency electromagnetic radiation on DNA integrity in the male germline.
R. Aitken et al. (2005) - 315 citations
- Thermal therapy, part 1: an introduction to thermal therapy.
R. Habash et al. (2006) - 296 citations
- 5G Wireless Communication and Health Effects—A Pragmatic Review Based on Available Studies Regarding 6 to 100 GHz
M. Simkó, M. Mattsson (2019) - 172 citations
- Radio-frequency radiation exposure from AM radio transmitters and childhood leukemia and brain cancer.
M. Ha et al. (2007) - 101 citations
- Biological effects of radiofrequency/microwave radiation
E. Adair, R. Petersen (2002) - 98 citations
- The Effect of Chronic Exposure to 835.62 MHz FDMA or 847.74 MHz CDMA Radiofrequency Radiation on the Incidence of Spontaneous Tumors in Rats
M. L. La Regina et al. (2003) - 60 citations