Radiofrequency radiation (900 MHz)-induced DNA damage and cell cycle arrest in testicular germ cells in swiss albino mice
Pandey N, Giri S, Das S, Upadhaya P · 2017
Radiofrequency radiation at 900 MHz induced reversible but significant impairment of spermatogenesis in mice through oxidative stress and cell cycle disruption.
Plain English Summary
This study examined the effects of 900 MHz radiofrequency radiation exposure on testicular germ cells in Swiss albino mice over 35 days. The researchers found that RFR exposure caused DNA damage, mitochondrial depolarization, cell cycle arrest at the premeiotic stage, and reduced sperm count, though these effects partially recovered during a 35-day post-exposure period.
Why This Matters
This study contributes to the literature on potential biological effects of mobile phone radiation by examining mechanisms at the cellular level. The finding of reversibility during recovery is noteworthy, though results in mice may not directly translate to human physiology and exposure patterns differ from typical mobile phone usage.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{pandey_n_giri_s_das_s_upadhaya_p_ce2963,
author = {Pandey N and Giri S and Das S and Upadhaya P},
title = {Radiofrequency radiation (900 MHz)-induced DNA damage and cell cycle arrest in testicular germ cells in swiss albino mice},
year = {2017},
doi = {10.1103/PhysRevLett.118.231801},
}