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DNA damage in Molt-4 T- lymphoblastoid cells exposed to cellular telephone radiofrequency fields in vitro

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Phillips, J.L., Ivaschuk, O., Ishida-Jones, T., Jones, R.A., Campbell-Beachler, M. and Haggren, W. · 1998

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Cell phone radiation caused DNA damage at levels 1,000 times below normal phone use, with effects varying dramatically by exposure intensity.

Plain English Summary

Summary written for general audiences

Researchers exposed immune cells to cell phone radiation at different power levels and measured DNA damage. They found that very low levels of radiation actually reduced DNA damage, while slightly higher levels increased it. This suggests that cell phone radiation can affect DNA in ways that depend on the specific exposure level.

Why This Matters

This study reveals a critical finding that challenges simple assumptions about EMF safety: the biological effects of radiofrequency radiation aren't always linear. The researchers found that extremely low SAR levels (2.4-2.6 μW/g) actually appeared protective, while levels just ten times higher (24-26 μW/g) caused DNA damage. To put this in perspective, these exposure levels are far below what your phone produces during a call (typically 0.5-2.0 W/kg, or roughly 1,000 times higher). What makes this research particularly significant is that it demonstrates measurable biological effects at power levels previously considered negligible. The non-linear dose response pattern suggests our cells have complex mechanisms for responding to EMF that we're only beginning to understand. This type of hormetic response - where low doses have opposite effects from higher doses - has been observed with other environmental exposures and underscores why we need more nuanced research rather than simple 'safe or not safe' conclusions.

Exposure Details

SAR
0.0024 & 0.024 W/kg
Source/Device
813.5625 MHz (iDEN® signal)
Exposure Duration
2 h or 21 h

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 0.0024 & 0.024 W/kgExtreme Concern0.1 W/kgFCC Limit1.6 W/kgEffects observed in the Slight Concern range (Building Biology)FCC limit is 667x higher than this exposure level

Study Details

To detect DNA damage in Molt-4 T-lymphoblastoid cells exposed to cellular telephone radiofrequency fields in vitro.

Molt-4 T-lymphoblastoid cells have been exposed to pulsed signals at cellular telephone frequencies ...

It was found that: 1) exposure of cells to the iDEN® signal at an SAR of 2.4 μW g−1 for 2 h or 21 h ...

The data indicate a need to study the effects of exposure to RF signals on direct DNA damage and on the rate at which DNA damage is repaired.

Cite This Study
Phillips, J.L., Ivaschuk, O., Ishida-Jones, T., Jones, R.A., Campbell-Beachler, M. and Haggren, W. (1998). DNA damage in Molt-4 T- lymphoblastoid cells exposed to cellular telephone radiofrequency fields in vitro Bioelectrochem. Bioenerg. 45:103-110, 1998.
Show BibTeX
@article{phillips_1998_dna_damage_in_molt4_49,
  author = {Phillips and J.L. and Ivaschuk and O. and Ishida-Jones and T. and Jones and R.A. and Campbell-Beachler and M. and Haggren and W.},
  title = {DNA damage in Molt-4 T- lymphoblastoid cells exposed to cellular telephone radiofrequency fields in vitro},
  year = {1998},
  
  url = {http://www.sciencedirect.com/science/article/pii/S0302459898000749},
}

Quick Questions About This Study

Researchers exposed immune cells to cell phone radiation at different power levels and measured DNA damage. They found that very low levels of radiation actually reduced DNA damage, while slightly higher levels increased it. This suggests that cell phone radiation can affect DNA in ways that depend on the specific exposure level.