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Detection of Low Level Microwave Radiation Induced Deoxyribonucleic Acid Damage Vis-à-vis Genotoxicity in Brain of Fischer Rats

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Deshmukh PS, Megha K, Banerjee BD, Ahmed RS, Chandna S, Abegaonkar MP, Tripathi AK · 2013

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Researchers found that low-level microwave radiation at 900, 1800, and 2450 MHz may induce DNA strand breaks in the brain tissue of Fischer rats.

Plain English Summary

Summary written for general audiences

The study investigated possible DNA-damaging effects of low-level microwave radiation in the brains of male Fischer rats. Rats were exposed for 30 days at three frequencies: 900, 1800, and 2450 MHz, at specific absorption rates on the order of 10−4 W/kg. DNA damage in brain tissue was assessed using alkaline comet assay after the exposure period. The researchers concluded that low SAR microwave radiation at these frequencies may induce DNA strand breaks in brain tissue.

Why This Matters

The study included a sham-exposed control group kept under the same conditions as the exposed animals but not exposed to microwave radiation. Each exposed group was assigned a distinct frequency, with SAR values of 5.953 × 10−4 W/kg at 900 MHz, 5.835 × 10−4 W/kg at 1800 MHz, and 6.672 × 10−4 W/kg at 2450 MHz. At the end of the exposure period, animals were sacrificed immediately and brain tissue was then analyzed. The researchers stated that they demonstrated DNA damaging effects of low level microwave radiation in brain.

Exposure Details

SAR
0.0005953 ,0.0005835 , 0.0006672 W/kg
Source/Device
900, 1800 and 2450 MHz
Exposure Duration
2 h/day, 5 days a week for 30 days

Where This Falls on the Concern Scale

Study Exposure Level in ContextStudy Exposure Level in ContextThis study: 0.0005953 ,0.0005835 , 0.0006672 W/kgExtreme Concern - 0.1 W/kgFCC Limit - 1.6 W/kgEffects documented below the Building Biology "No Concern" threshold (0.001 W/kg)FCC limit is 2,742 times higher than this level
A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.45 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.45 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Study Details

The present study was designed to investigate the possible deoxyribonucleic acid (DNA) damaging effects of low-level microwave radiation in brain of Fischer rats

Experiments were performed on male Fischer rats exposed to microwave radiation for 30 days at three ...

In the present study, we demonstrated DNA damaging effects of low level microwave radiation in brain...

We concluded that low SAR microwave radiation exposure at these frequencies may induce DNA strand breaks in brain tissue.

Cite This Study
Deshmukh PS, Megha K, Banerjee BD, Ahmed RS, Chandna S, Abegaonkar MP, Tripathi AK (2013). Detection of Low Level Microwave Radiation Induced Deoxyribonucleic Acid Damage Vis-à-vis Genotoxicity in Brain of Fischer Rats Toxicol Int. 20(1):19-24, 2013b.
Show BibTeX
@article{ps_2013_detection_of_low_level_92,
  author = {Deshmukh PS and Megha K and Banerjee BD and Ahmed RS and Chandna S and Abegaonkar MP and Tripathi AK},
  title = {Detection of Low Level Microwave Radiation Induced Deoxyribonucleic Acid Damage Vis-à-vis Genotoxicity in Brain of Fischer Rats},
  year = {2013},
  
  url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702122/},
}

Quick Questions About This Study

The study used male Fischer rats exposed to microwave radiation for 30 days.
Three frequencies were tested: 900, 1800, and 2450 MHz.
DNA damage in brain tissue was assessed using alkaline comet assay.
The researchers concluded that low SAR microwave radiation exposure at these frequencies may induce DNA strand breaks in brain tissue.
A sham-exposed group was included, consisting of animals not exposed to microwave radiation but kept under the same conditions as the other groups.