Induction of Poly(ADP-ribose) Polymerase in Mouse Bone Marrow Stromal Cells Exposed to 900 MHz Radiofrequency Fields: Preliminary Observations.
He Q, Sun Y, Zong L, Tong J, Cao Y. · 2016
View Original AbstractRF radiation at cell phone levels activated DNA repair mechanisms in bone marrow cells, suggesting cellular damage occurs even at 'safe' exposure levels.
Plain English Summary
Researchers exposed mouse bone marrow cells to cell phone-level radiation for three hours daily over five days. The cells showed significant increases in PARP-1, a protein that repairs DNA damage, suggesting the radiation triggered cellular stress requiring DNA repair mechanisms.
Why This Matters
This study reveals something important about how our cells respond to radiofrequency radiation at power levels you encounter daily. The 120 μW/cm² exposure used here is actually lower than what your phone produces during a call, yet it still triggered DNA repair mechanisms in bone marrow cells. PARP-1 activation is essentially your cell's emergency response system for DNA damage. The fact that RF radiation activated this repair system suggests the radiation was causing some level of cellular stress or damage, even at these relatively modest power levels. What makes this research particularly significant is that bone marrow produces your blood cells and immune system components. While this is preliminary research on mouse cells, it adds to the growing body of evidence that RF radiation isn't as biologically inert as the wireless industry claims. The science demonstrates that our cells are responding to these exposures in measurable ways.
Exposure Details
- Power Density
- 0.12 µW/m²
- Source/Device
- 900 MHz
- Exposure Duration
- 3 hours/day for 5 days.
Exposure Context
This study used 0.12 µW/m² for radio frequency:
- 12Mx above the Building Biology guideline of 0.1 μW/m²
- 200Kx above the BioInitiative Report recommendation of 0.0006 μW/cm²
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
To examine whether exposure of the cells to nonionizing radiofrequency fields (RF) is capable of increasing messenger RNA of PARP-1 and its protein levels in mouse bone marrow stromal cells (BMSCs).
BMSCs were exposed to 900 MHz RF at 120 μW/cm(2) power intensity for 3 hours/day for 5 days. PARP-1 ...
BMSCs exposed to RF showed significantly increased expression of PARP-1 mRNA and its protein levels ...
Nonionizing RF exposure is capable of inducing PARP-1.
Show BibTeX
@article{q_2016_induction_of_polyadpribose_polymerase_1019,
author = {He Q and Sun Y and Zong L and Tong J and Cao Y.},
title = {Induction of Poly(ADP-ribose) Polymerase in Mouse Bone Marrow Stromal Cells Exposed to 900 MHz Radiofrequency Fields: Preliminary Observations.},
year = {2016},
url = {https://pubmed.ncbi.nlm.nih.gov/27190989/},
}