8,700 Studies Reviewed. 87.0% Found Biological Effects. The Evidence is Clear.
Shield Your Body

Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Cancer & Tumors

Radiofrequency electromagnetic fields have no effect on the in vivo proliferation of the 9L brain tumor.

No Effects Found

Higashikubo R, Culbreth VO, Spitz DR, LaRegina MC, Pickard WF, Straube WL, Moros EG, Roti JL, · 1999

View Original Abstract
Share:

RF radiation at cell phone levels didn't accelerate brain tumor growth in rats, but this doesn't address whether it causes tumors initially.

Plain English Summary

Summary written for general audiences

Researchers exposed rats with brain tumors to cell phone-like radiofrequency radiation for 4 hours daily over several months to see if the radiation would affect tumor growth. The study found no difference in survival rates between rats exposed to RF radiation and those that weren't exposed. This suggests that RF radiation at levels similar to cell phones doesn't accelerate brain tumor growth in this animal model.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 835.6 MHz - 847.7 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 835.6 MHz - 847.7 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 835.62 MHz or 847.74 MHz Duration: 4 h a day, 5 days a week

Study Details

The intracranial 9L tumor model was used to determine if exposure to a radiofrequency (RF) electromagnetic field similar to those used in cellular telephone has any effects on the growth of a central nervous system tumor

Fischer 344 rats implanted with different numbers of 9L gliosarcoma cells were exposed to 835.62 MHz...

The median survival length and final survival fraction for animals injected with 11 to 36 viable cel...

Cite This Study
Higashikubo R, Culbreth VO, Spitz DR, LaRegina MC, Pickard WF, Straube WL, Moros EG, Roti JL, (1999). Radiofrequency electromagnetic fields have no effect on the in vivo proliferation of the 9L brain tumor. Radiat Res 152(6):665-671, 1999.
Show BibTeX
@article{r_1999_radiofrequency_electromagnetic_fields_have_3080,
  author = {Higashikubo R and Culbreth VO and Spitz DR and LaRegina MC and Pickard WF and Straube WL and Moros EG and Roti JL and},
  title = {Radiofrequency electromagnetic fields have no effect on the in vivo proliferation of the 9L brain tumor.},
  year = {1999},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/10581537/},
}
PubMed: 10581537

Cited By (38 papers)

Quick Questions About This Study

No, 835 MHz radiofrequency radiation does not accelerate brain tumor growth in rats. A 1999 study exposed rats with brain tumors to cell phone-like radiation for 4 hours daily over several months and found no difference in survival rates compared to unexposed rats.
CDMA frequency radiation does not make existing brain tumors grow faster. Research using 835.62 MHz and 847.74 MHz frequencies found identical survival rates between rats exposed to CDMA radiation and control groups, with median survival times of 45-52 days regardless of exposure.
Four hours of daily RF exposure does not affect brain tumor survival in animals. Rats exposed to radiofrequency radiation for 4 hours daily showed the same survival parameters as unexposed controls, with no significant differences in median survival length or final survival rates.
Based on animal studies, 847.74 MHz radiation does not appear dangerous for existing brain tumors. Rats with brain tumors exposed to this frequency showed identical survival outcomes to unexposed rats, suggesting this radiation level doesn't accelerate tumor progression in this model.
FMCW radar frequencies do not worsen brain tumor outcomes in laboratory studies. Research found that rats exposed to frequency-modulated continuous wave radiation had similar survival parameters to control groups, with no statistically significant differences in tumor progression or survival rates.