Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.
Radiofrequency radiation does not significantly affect ornithine decarboxylase activity, proliferation, or caspase-3 activity of fibroblasts in different physiological conditions
Authors not listed · 2008
Radiofrequency radiation at 872 MHz and 5 W/kg did not significantly affect ornithine decarboxylase activity, proliferation, or caspase-3 activity in murine fibroblasts under different physiological conditions.
Plain English Summary
Researchers exposed murine L929 fibroblasts to 872 MHz continuous wave or pulse modulated RF radiation at 5 W/kg. They measured ornithine decarboxylase activity after 1- and 24-hour exposures, proliferation during 48 hours after 24-hour exposure, and caspase-3 activity after 1-hour exposure. The cells responded to fresh medium and serum deprivation, but no consistent effects of RF radiation were found. One statistically significant difference in ODC activity (p=0.03) was observed but considered a chance finding due to multiple comparisons and lack of support from other data. The results did not support effects on the endpoints studied, and stressed or stimulated cells were not more sensitive than normal cells to RF radiation.
Why This Matters
The study was designed to test whether variations in the physiological state of cells explain inconsistent results from previous in vitro studies on radiofrequency radiation effects. The researchers concluded that radiofrequency radiation does not significantly affect ornithine decarboxylase activity, proliferation, or caspase-3 activity of fibroblasts in different physiological conditions.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{radiofrequency_radiation_does_not_significantly_affect_ornithine_decarboxylase_activity_proliferation_or_caspase_3_activity_of_fibroblasts_in_different_physiological_conditions_ce906,
author = {Unknown},
title = {Radiofrequency radiation does not significantly affect ornithine decarboxylase activity, proliferation, or caspase-3 activity of fibroblasts in different physiological conditions},
year = {2008},
doi = {10.1080/09553000802345928},
}