Regulation of myogenesis and adipogenesis by the electromagnetic perceptive gene
Authors not listed · 2023
In vivo experiments showed that EPG with magnetic field decreased total weight, fat, and fat accumulation and increased lean mass in mice, with effects depending on age.
Plain English Summary
Researchers investigated whether the electromagnetic perceptive gene (EPG) could serve as a therapeutic method against obesity. They confirmed that EPG modulates Ca2+ levels in primary adipose cells and regulates genes such as CasR, PPARγ, GLU4, and GAPDH during adipogenesis. The study also found that EPG changed myocyte transcription factors including CasR, MyoG, MyoD, and Myomaker in C2C12 cells and satellite cells. In vivo experiments showed that EPG with magnetic field decreased total weight, fat, and fat accumulation and increased lean mass in mice, with effects depending on age.
Why This Matters
Previous research had shown that the electromagnetic perceptive gene regulates intracellular calcium levels under various electromagnetic fields. The authors concluded that EPG could serve as a potent therapeutic agent against obesity.
Show BibTeX
@article{regulation_of_myogenesis_and_adipogenesis_by_the_electromagnetic_perceptive_gene_ce4053,
author = {Unknown},
title = {Regulation of myogenesis and adipogenesis by the electromagnetic perceptive gene},
year = {2023},
}