6,486 Studies Reviewed. 85.2% of Original Studies Found Biological Effects. The Evidence is Clear.

Note: This study found no significant biological effects under its experimental conditions. We include all studies for scientific completeness.

Effects of GSM-modulated 900 MHz radiofrequency electromagnetic fields on the hematopoietic potential of mouse bone marrow cells

No Effects Found

Rosado MM et al · 2014

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In vivo exposure to GSM-modulated 900 MHz RF fields had no effect on the ability of bone marrow precursors to long-term reconstitute peripheral T and B cell compartments.

Plain English Summary

Summary written for general audiences

Researchers exposed mice to GSM-modulated 900 MHz RF fields and transplanted bone marrow cells into irradiated syngeneic recipients from exposed, sham-exposed, or cage control donors. Twelve weeks later, thymocyte numbers, subpopulation frequencies, cell proliferation, spleen cell counts, B/T cell percentages, B/T proliferation, and IFN-γ production were all similar across groups. In a competitive transplant into Rag2-deficient mice, marrow from RF-exposed and sham-exposed mice performed equally, though both were less effective than cage-control marrow, an effect the authors linked to restraint stress, and they concluded that GSM-modulated RF exposure did not impair long-term reconstitution of peripheral T and B cell compartments.

Why This Matters

The authors noted that previous studies of radiofrequency electromagnetic fields on bone marrow cells often lack functional data. The study was published in Bioelectromagnetics in 2014.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 900 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 900 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Rosado MM et al (2014). Effects of GSM-modulated 900 MHz radiofrequency electromagnetic fields on the hematopoietic potential of mouse bone marrow cells.
Show BibTeX
@article{rosado_mm_et_al_september_2014_effects_of_gsm_modulated_900_mhz_radiofrequency_electromagnetic_fields_on_the_hematopoietic_potential_of_mouse_bone_marrow_cells_bioelectromagnetics_ce635,
  author = {Rosado MM et al},
  title = {Effects of GSM-modulated 900 MHz radiofrequency electromagnetic fields on the hematopoietic potential of mouse bone marrow cells},
  year = {2014},
  doi = {10.1002/bem.21880},
  
}

Quick Questions About This Study

The study used in vivo exposure to GSM-modulated 900 MHz radiofrequency fields.
One model transplanted bone marrow cells into irradiated syngeneic mice. The other model co-transplanted a mixture of bone marrow from sham-exposed and RF-exposed mice into lymphopenic Rag2-deficient mice.
Twelve weeks after transplantation, no differences in thymocyte number, subpopulation frequencies, or cell proliferation were observed among the groups.
Bone marrow from RF-exposed and sham-exposed mice showed no advantage or disadvantage in replenishing lymphatic organs, although both were less efficient than cage control marrow, an effect attributed to restraint stress.
The authors concluded that in vivo exposure to GSM-modulated RF fields did not affect the long-term ability of bone marrow precursors to reconstitute peripheral T and B cell compartments.