Extremely low frequency magnetic field induced changes in motor behaviour of gerbils submitted to global cerebral ischemia.
Rauš S, Selaković V, Radenović L, Prolić Z, Janać B. · 2012
View Original AbstractA 50 Hz, 0.5 mT magnetic field reduced the motor hyperactivity seen in gerbils after global cerebral ischemia, most notably in the first two days after reperfusion.
Plain English Summary
Researchers studied how an extremely low frequency magnetic field affects motor behaviour in 3-month-old Mongolian gerbils that had undergone global cerebral ischemia. After a 10-minute blockage of both common carotid arteries, gerbils were continuously exposed to ELF-MF at 50 Hz and 0.5 mT for 7 days, and their behaviour was monitored on days 1, 2, 4, 7, and 14 after reperfusion. Ischemia alone caused significant increases in locomotion, stereotypy, and rotations, along with decreased immobility, up to day 4 after reperfusion compared to control gerbils. ELF-MF exposure inhibited ischemia-induced motor hyperactivity throughout the observation period, though significantly only in the first 2 days after reperfusion.
Why This Matters
The gerbils' behaviour was observed in an open field for 60 minutes at each time point, covering locomotion, stereotypy, rotations, and immobility. Even with ELF-MF exposure, motor activity of the ischemic gerbils was still significantly increased compared to controls, but only on day 1 after reperfusion. The researchers described the ELF-MF effect as working via modulation of the processes that underlie the behavioural response to ischemia.
Exposure Details
- Magnetic Field
- 0.5 mT
- Source/Device
- 50 Hz
- Exposure Duration
- 7 days
Exposure Context
This study used 0.5 mT for magnetic fields:
- 25Kx above the Building Biology guideline of 0.2 mG
- 5Kx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
The purpose of this study was to evaluate behavioural effects of an extremely low frequency magnetic field (ELF-MF) in 3-month-old Mongolian gerbils submitted to global cerebral ischemia
After 10-min occlusion of both common carotid arteries, the gerbils were placed in the vicinity of a...
It was shown that the 10-min global cerebral ischemia per se induced a significant motor activity in...
Our results revealed that the applied ELF-MF (50 Hz, 0.5 mT) decreased motor hyperactivity induced by the 10-min global cerebral ischemia, via modulation of the processes that underlie this behavioural response.
Show BibTeX
@article{s_2012_extremely_low_frequency_magnetic_285,
author = {Rauš S and Selaković V and Radenović L and Prolić Z and Janać B.},
title = {Extremely low frequency magnetic field induced changes in motor behaviour of gerbils submitted to global cerebral ischemia.},
year = {2012},
url = {https://www.sciencedirect.com/science/article/abs/pii/S0166432811007790},
}