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Study of p53 expression and post-transcriptional modifications after GSM-900 radiofrequency exposure of human amniotic cells.

No Effects Found

Bourthoumieu S, Magnaudeix A, Terro F, Leveque P, Collin A, Yardin C. · 2012

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GSM cell phone radiation didn't activate p53 tumor suppressor protein in embryonic cells at levels up to double current phone SAR limits.

Plain English Summary

Summary written for general audiences

Researchers exposed human embryonic cells to cell phone radiation (GSM-900 MHz) for 24 hours at various intensities to see if it would activate p53, a crucial protein that helps protect cells from DNA damage and cancer. The study found no significant changes in p53 expression or activation at any exposure level tested, including levels up to 4 W/kg. This suggests that GSM cell phone radiation may not trigger this particular cellular stress response in embryonic cells.

Study Details

The objective of this study was to investigate whether the exposure to RF electromagnetic fields, similar to those emitted by mobile phones of the second generation standard, Global System for Mobile Communications (GSM), may induce expression of the p53 protein and its activation by post-translational modifications in cultured human cells.

The potential induction of p53 expression and activation by GSM-900 was investigated after in vitro ...

According to our results, no significant changes in the expression and activation of the p53 protein...

Cite This Study
Bourthoumieu S, Magnaudeix A, Terro F, Leveque P, Collin A, Yardin C. (2012). Study of p53 expression and post-transcriptional modifications after GSM-900 radiofrequency exposure of human amniotic cells. Bioelectromagnetics. 2012 Jul 5. doi: 10.1002/bem.21744.
Show BibTeX
@article{s_2012_study_of_p53_expression_2961,
  author = {Bourthoumieu S and Magnaudeix A and Terro F and Leveque P and Collin A and Yardin C.},
  title = {Study of p53 expression and post-transcriptional modifications after GSM-900 radiofrequency exposure of human amniotic cells.},
  year = {2012},
  doi = {10.1002/bem.21744},
  url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/bem.21744},
}

Quick Questions About This Study

Researchers exposed human embryonic cells to cell phone radiation (GSM-900 MHz) for 24 hours at various intensities to see if it would activate p53, a crucial protein that helps protect cells from DNA damage and cancer. The study found no significant changes in p53 expression or activation at any exposure level tested, including levels up to 4 W/kg. This suggests that GSM cell phone radiation may not trigger this particular cellular stress response in embryonic cells.