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Risk of neuroblastoma, maternal characteristics and perinatal exposures: The SETIL study.

No Effects Found

Parodi S, Merlo DF, Ranucci A, Miligi L, Benvenuti A, Rondelli R, Magnani C, Haupt R · 2014

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Home magnetic field measurements showed no link to childhood neuroblastoma, adding evidence that ELF fields may not drive cancer risk.

Plain English Summary

Summary written for general audiences

Italian researchers studied 153 children with neuroblastoma (a childhood cancer) and 1044 healthy children to identify risk factors. They measured extremely low frequency magnetic fields (ELF-MF) in homes and found no association between magnetic field exposure and neuroblastoma risk. However, they did find increased cancer risk linked to maternal exposure to hair dyes and workplace chemicals during pregnancy.

Study Details

Neuroblastoma (NB) is the most common extra-cranial paediatric solid tumour. Incidence peaks in infancy, suggesting a role of in-utero and neonatal exposures but its aetiology is largely unknown. The aim of the present study is to evaluate the association between maternal characteristics and perinatal factors with the risk of NB, using data from the SETIL database.

SETIL is a large Italian population-based case-control study established to evaluate several potenti...

A twofold risk was associated to exposure in pregnancy to chemical products for domestic work and to...

Our study suggests maternal exposure to hair dyes and aromatic hydrocarbons plays a role and deserves further investigation. The association with congenital malformations might also be explained by over-diagnosis. External exposure, in particular during and before pregnancy might contribute to NB occurrence.

Cite This Study
Parodi S, Merlo DF, Ranucci A, Miligi L, Benvenuti A, Rondelli R, Magnani C, Haupt R (2014). Risk of neuroblastoma, maternal characteristics and perinatal exposures: The SETIL study. Cancer Epidemiol. 2014 Sep 30. pii: S1877-7821(14)00157-X. doi: 10.1016/j.canep.2014.09.007.
Show BibTeX
@article{s_2014__risk_of_neuroblastoma_3299,
  author = {Parodi S and Merlo DF and Ranucci A and Miligi L and Benvenuti A and Rondelli R and Magnani C and Haupt R},
  title = { Risk of neuroblastoma, maternal characteristics and perinatal exposures: The SETIL study. },
  year = {2014},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/25280392/},
}

Quick Questions About This Study

Italian researchers studied 153 children with neuroblastoma (a childhood cancer) and 1044 healthy children to identify risk factors. They measured extremely low frequency magnetic fields (ELF-MF) in homes and found no association between magnetic field exposure and neuroblastoma risk. However, they did find increased cancer risk linked to maternal exposure to hair dyes and workplace chemicals during pregnancy.