Neuroprotective effects of dietary supplement Kang-fu-ling against high-power microwave through antioxidant action
Hu S, Peng R, Wang C, Wang S, Gao Y, Dong J, Zhou H, Su Z, Qiao S, Zhang S, Wang L, Wen X · 2014
View Original AbstractThe dietary supplement Kang-fu-ling (KFL) reversed memory loss and oxidative stress in rats exposed to high-power microwave.
Plain English Summary
Researchers exposed male Wistar rats to high-power microwave at 30 mW cm−2 for 15 minutes, then administered the dietary supplement KFL orally once daily for 14 days. KFL reversed high-power microwave-induced memory loss and histopathological changes in the hippocampus of rats. KFL also displayed a protective effect against high-power microwave-induced oxidative stress and activated the Nrf2 signaling pathway and its target genes in the hippocampus.
Why This Matters
The study aimed to evaluate the potential protective effects of KFL on cognitive deficits induced by high-power microwave and the underlying mechanism for this neuroprotection. KFL was tested in vitro for free radical scavenging using the electron spin resonance technique and was found to exhibit hydroxyl radical scavenging activity. The researchers suggested that the Nrf2-antioxidant response element signaling pathway may be involved in the neuroprotective effects of KFL against high-power microwave-induced oxidative stress.
Exposure Details
- SAR
- 21 W/kg
- Power Density
- 30 mW/cm²
- Exposure Duration
- 15 minutes
Exposure Context
This study used 30 mW/cm² for radio frequency:
- 3,000Mx above the Building Biology guideline of 0.1 μW/m²
- 50Mx above the BioInitiative Report recommendation of 0.0006 μW/cm²
This study used 21 W/kg for SAR (device absorption):
- 52.5x above the Building Biology guideline of 0.4 W/kg
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
This study aimed to evaluate the potential protective effects of KFL on cognitive deficit induced by high-power microwave (HPM) and the underlying mechanism for this neuroprotection.
The electron spin resonance technique was employed to evaluate the free radical scavenging activity ...
KFL reversed HPM-induced memory loss and the histopathological changes in hippocampus of rats. In ad...
In summary, the dietary supplement KFL is a promising natural complex, which ameliorates oxidative stress, with neuroprotective effects against HPM.
Show BibTeX
@article{s_2014_neuroprotective_effects_of_dietary_108,
author = {Hu S and Peng R and Wang C and Wang S and Gao Y and Dong J and Zhou H and Su Z and Qiao S and Zhang S and Wang L and Wen X},
title = {Neuroprotective effects of dietary supplement Kang-fu-ling against high-power microwave through antioxidant action},
year = {2014},
url = {https://pubs.rsc.org/en/content/articlelanding/2014/fo/c4fo00257a/unauth#!divAbstract},
}