Vitamin E prevents glucose metabolism alterations induced by static magnetic field in rats

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Ghodbane S1, Amara S, Lahbib A, Louchami K, Sener A, Sakly M, Abdelmelek H. · 2014

Vitamin E prevented blood glucose and liver glycogen changes caused by static magnetic field exposure in rats, while selenium restored only liver glycogen.

Plain English Summary

Summary written for general audiences

Researchers exposed rats to a static magnetic field of 128 mT for one hour per day over five days and examined effects on glucose metabolism. Exposure increased blood glucose level by 21% and caused a decrease of 15% in liver glycogen content. Vitamin E prevented the glucose metabolism and liver glycogen alterations induced by the static magnetic field, whereas selenium restored only liver glycogen content. Neither vitamin E nor selenium corrected the reduction in pancreatic islet area observed after static magnetic field exposure.

Why This Matters

The study investigated whether vitamin E or selenium could protect against glucose metabolism disruption induced by static magnetic field exposure in rats. The static magnetic field did not alter body weight or relative liver weight in exposed rats. Vitamin E was given orally at 150 mg/kg for five days, while selenium was provided in drinking water at 0.20 mg/l for four weeks. While vitamin E offered broader protection across glucose metabolism outcomes, selenium's protective effect was limited to hepatic glycogen content. The reduction in pancreatic islet area was not corrected by either supplement.

Exposure Details

Magnetic Field: 128 mT
Exposure Duration: 1 h/day during 5 days

Exposure Context

This study used 128 mT for magnetic fields:

6.4Mx above the Building Biology guideline of 0.2 mG
1.3Mx above the BioInitiative Report recommendation of 1 mG

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Details

In the present study, we investigate the effects of a possible protective role of vitamin E (vit E) or selenium (Se) on glucose metabolism disruption induced by static magnetic field (SMF) in rats.

Rats have been exposed to SMF (128 mT, 1 h/day during 5 days).

Our results showed that SMF failed to alter body weight and relative liver weight. Our data demonstr...

Cite This Study

Ghodbane S1, Amara S, Lahbib A, Louchami K, Sener A, Sakly M, Abdelmelek H. (2014). Vitamin E prevents glucose metabolism alterations induced by static magnetic field in rats Environ Sci Pollut Res Int. 21(22):12731-12738, 2014.

Show BibTeX

@article{s1_2014_vitamin_e_prevents_glucose_372,
  author = {Ghodbane S1 and Amara S and Lahbib A and Louchami K and Sener A and Sakly M and Abdelmelek H. },
  title = {Vitamin E prevents glucose metabolism alterations induced by static magnetic field in rats},
  year = {2014},
  doi = {10.1007/s11356-014-3224-x},
  url = {https://link.springer.com/article/10.1007/s11356-014-3224-x},
}

DOI: 10.1007/s11356-014-3224-x

Cited By (2 papers)

Homogeneous static magnetic field of different orientation induces biological changes in subacutely exposed mice
Ivan D. Milovanovich et al. (2015) - 38 citations
Duration-dependent effect of exposure to static electric field on learning and memory ability in mice
Yaqian Xu et al. (2018) - 8 citations

Quick Questions About This Study

Exposure to the static magnetic field increased blood glucose level by 21%.

Static magnetic field exposure caused a decrease of 15% in liver glycogen content.

Vitamin E prevented alterations in glucose metabolism and liver glycogen content, but failed to correct the reduction in pancreatic islet area.

Selenium restored only hepatic glycogen contents and did not prevent the broader glucose metabolism alterations.

The static magnetic field failed to alter body weight and relative liver weight.