Effects of continuous prenatal and postnatal global system for mobile communications electromagnetic waves (GSM-EMW) exposure on the oxidative stress biomarkers in female rat liver
Authors not listed · 2022
Continuous prenatal and postnatal exposure to 900 MHz GSM-modulated RF-EMR increased oxidative stress markers in the liver of female Sprague-Dawley rats at postnatal days 1, 9, and 21.
Plain English Summary
Researchers continuously exposed pregnant Sprague-Dawley rats and their offspring to 900 MHz GSM-modulated RF-EMR for 24 hours per day and assessed liver oxidative stress at postnatal days 1, 9, and 21. Exposure significantly raised MDA levels at PND9 and PND21, lowered catalase activity at all ages, reduced catalase amount and mRNA at PND1 and PND9, and decreased GPx activity at PND21. CytoSOD levels increased at PND9 and 21 while mitoSOD levels decreased at PND21, and both GPx level and mitoSOD activity were elevated at all ages. SOD1 mRNA expression rose at PND1 but fell at PND9 and 21, whereas GPx1 expression was consistently reduced in the exposed group.
Why This Matters
CytoSOD activity was significantly reduced at PND1 but increased at PND9 in the exposed rats. Exposed rats displayed a similar expression pattern for Akt1, Nrf-2, and ICAM-1 at PND1 and PND9.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{effects_of_continuous_prenatal_and_postnatal_global_system_for_mobile_communications_electromagnetic_waves_gsm_emw_exposure_on_the_oxidative_stress_biomarkers_in_female_rat_liver_ce2578,
author = {Unknown},
title = {Effects of continuous prenatal and postnatal global system for mobile communications electromagnetic waves (GSM-EMW) exposure on the oxidative stress biomarkers in female rat liver},
year = {2022},
doi = {10.1016/j.heliyon.2022.e12367},
}