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Sulforaphane Effects on Neuronal-like Cells and Peripheral Blood Mononuclear Cells Exposed to 2.45 GHz Electromagnetic Radiation

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Authors not listed · 2024

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A 24-hour exposure to 2.45 GHz EMR reduced viability of SH-SY5Y neuronal-like cells and PBMCs, and 5 µg/mL sulforaphane protected the cells while higher concentrations were harmful.

Plain English Summary

Summary written for general audiences

Researchers exposed SH-SY5Y neuronal-like cells and peripheral blood mononuclear cells to 2.45 GHz EMR for 24 hours with sulforaphane at 5, 10, and 25 µg/mL. Higher sulforaphane concentrations caused harmful effects and the compound showed a hormetic response in Nrf2, SOD2, and apoptosis markers.

Why This Matters

The authors note that 2.45 GHz EMR from common devices has been reported to cause oxidative stress in experimental models. The study measured cell viability, mitochondrial activity, redox-marker transcription and protein levels, and apoptosis-related genes.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2.45 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2.45 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Unknown (2024). Sulforaphane Effects on Neuronal-like Cells and Peripheral Blood Mononuclear Cells Exposed to 2.45 GHz Electromagnetic Radiation.
Show BibTeX
@article{sulforaphane_effects_on_neuronal_like_cells_and_peripheral_blood_mononuclear_cells_exposed_to_245_ghz_electromagnetic_radiation_ce2317,
  author = {Unknown},
  title = {Sulforaphane Effects on Neuronal-like Cells and Peripheral Blood Mononuclear Cells Exposed to 2.45 GHz Electromagnetic Radiation},
  year = {2024},
  doi = {10.3390/ijms25147872},
  
}

Quick Questions About This Study

The study used SH-SY5Y neuronal-like cells and peripheral blood mononuclear cells.
Cells were exposed to 2.45 GHz EMR for 24 hours.
EMR exposure caused a reduction in viability of both neuronal-like cells and PBMCs.
The lowest sulforaphane concentration (5 µg/mL) protected cells, decreased ROS production, and increased mitochondrial membrane potential and the NAD+/NADH ratio.
Sulforaphane at higher concentrations displayed harmful effects and showed a hormetic response in Nrf2, SOD2, and apoptosis markers.