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Cancer & Tumors

Lack of promoting effects of chronic exposure to 1.95-GHz W-CDMA signals for IMT-2000 cellular system on development of N-ethylnitrosourea-induced central nervous system tumors in F344 rats.

No Effects Found

Shirai T, Ichihara T, Wake K, Watanabe SI, Yamanaka Y, Kawabe M, Taki M, Fujiwara O, Wang J, Takahashi S, Tamano S. · 2007

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Two-year exposure to cell phone radiation at typical SAR levels did not promote brain tumor development in rats.

Plain English Summary

Summary written for general audiences

Researchers exposed young rats to cell phone-like radiation (1.95 GHz W-CDMA signals) for 2 years to see if it would promote brain tumor development in animals already given a cancer-causing chemical. The study found no significant increase in brain tumors from the radiation exposure at levels of 0.67 and 2.0 W/kg SAR. This suggests that chronic exposure to this type of cell phone radiation does not accelerate brain tumor formation in this animal model.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 1.95 GHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 1.95 GHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

The study examined exposure from: 1.95-GHz Duration: 90 min/day, 5 days/week, for 104 weeks

Study Details

The present study was performed to evaluate effects of a 2-year exposure to an electromagnetic near-field (EMF) equivalent to that generated by cellular phones on tumor development in the central nervous system (CNS) of rats.

For this purpose, pregnant F344 rats were given a single administration of N-ethylnitrosourea (ENU) ...

The incidence and numbers of brain tumors in female rats exposed to 1.95-GHz W-CDMA signals showed t...

Thus, under the present experimental conditions, exposure of heads of rats to 1.95-GHz W-CDMA signals for IMT-2000 for a 2-year period was not demonstrated to accelerate or otherwise affect ENU-initiated brain tumorigenesis.

Cite This Study
Shirai T, Ichihara T, Wake K, Watanabe SI, Yamanaka Y, Kawabe M, Taki M, Fujiwara O, Wang J, Takahashi S, Tamano S. (2007). Lack of promoting effects of chronic exposure to 1.95-GHz W-CDMA signals for IMT-2000 cellular system on development of N-ethylnitrosourea-induced central nervous system tumors in F344 rats. Bioelectromagnetics.28(7):562-572, 2007.
Show BibTeX
@article{t_2007_lack_of_promoting_effects_3395,
  author = {Shirai T and Ichihara T and Wake K and Watanabe SI and Yamanaka Y and Kawabe M and Taki M and Fujiwara O and Wang J and Takahashi S and Tamano S.},
  title = {Lack of promoting effects of chronic exposure to 1.95-GHz W-CDMA signals for IMT-2000 cellular system on development of N-ethylnitrosourea-induced central nervous system tumors in F344 rats.},
  year = {2007},
  
  url = {https://pubmed.ncbi.nlm.nih.gov/17516507/},
}
PubMed: 17516507

Cited By (37 papers)

Quick Questions About This Study

A 2-year study found that 1.95 GHz W-CDMA signals did not promote brain tumor development in rats. Researchers exposed animals to radiation at 0.67 and 2.0 W/kg SAR levels but found no significant increase in brain tumors compared to unexposed animals.
Research shows W-CDMA signals do not accelerate brain cancer development. Scientists gave rats a cancer-causing chemical then exposed them to 1.95 GHz W-CDMA radiation for two years, but found no significant increase in tumor formation or progression.
Researchers tested W-CDMA radiation at 0.67 W/kg and 2.0 W/kg SAR levels over two years. Neither exposure level significantly increased brain tumor incidence in rats that received cancer-promoting chemicals, suggesting these power levels don't accelerate tumor development.
Female rats showed slight tendencies toward increased brain tumors from 1.95 GHz W-CDMA exposure, but these increases were not statistically significant. The study found no clear differences between male and female responses to the radiation exposure.
Scientists exposed rats to 1.95 GHz W-CDMA signals for a full 2-year period to test long-term effects. This chronic exposure duration allowed researchers to assess whether prolonged cell phone-type radiation would promote brain tumor development in animals.