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The effects of short-term and long-term 2100 MHz radiofrequency radiation on adult rat auditory brainstem response

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Er H, Basaranlar G., Derin N., Kantar D, Ozen S. · 2025

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Acute 2100 MHz RFR exposure prolonged all auditory brainstem response wave latencies, raised oxidative stress markers, and lowered antioxidant enzyme activities, whereas chronic exposure with rest days showed no harmful effects.

Plain English Summary

Summary written for general audiences

Researchers exposed adult rats to 2100 MHz RFR for 2 hours per day, 5 days per week, for either 1 week or 10 weeks, with sham controls. In the 1-week exposure group, all auditory brainstem response wave latencies were prolonged, oxidative stress markers increased, and antioxidant enzyme activities decreased. Acute exposure also caused edema in neurons, astrocytes, and astrocytic end-feet, as well as mitochondrial damage in astrocytes. The 10-week exposure group showed no harmful effects on the auditory system.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 2100 MHz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 2100 MHzPower lines50/60 Hz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Er H, Basaranlar G., Derin N., Kantar D, Ozen S. (2025). The effects of short-term and long-term 2100 MHz radiofrequency radiation on adult rat auditory brainstem response.
Show BibTeX
@article{the_effects_of_short_term_and_long_term_2100_mhz_radiofrequency_radiation_on_adult_rat_auditory_brainstem_response_ce2363,
  author = {Er H and Basaranlar G. and Derin N. and Kantar D and Ozen S.},
  title = {The effects of short-term and long-term 2100 MHz radiofrequency radiation on adult rat auditory brainstem response},
  year = {2025},
  doi = {10.1515/chem-2025-0173},
  
}

Quick Questions About This Study

Rats were exposed to 2100 MHz RFR for 2 hours per day, 5 days per week, for either 1 week or 10 weeks, with sham controls.
Acute exposure prolonged the latencies of all auditory brainstem response waves compared to sham-exposed rats.
Acute exposure increased oxidative stress markers such as 4-hydroxynonenal, thiobarbituric acid reactive substances, and protein carbonyl, while decreasing catalase and superoxide dismutase activities.
Edema in neurons, astrocytes, and astrocytic end-feet, along with mitochondrial damage in astrocytes, was observed after acute exposure.
Chronic exposure with rest days showed no harmful effects on the auditory system.