The protective effect of melatonin on radiofrequency electromagnetic fields of mobile phone-induced testicular damage in an experimental mouse model
Authors not listed · 2020
Melatonin treatment improved oxidative stress parameters, testicular injury score, germinal epithelial thickness, seminiferous tubule diameter, and decreased testosterone in RF-EMR exposed mice.
Plain English Summary
The study used 32 adult male BALB/c mice divided into four groups: control, melatonin (2 mg/kg intraperitoneally for 30 consecutive days), RF-EMR exposure (900 MHz, 100 to 300 MT, 54 to 160 W/m, 4 hours per day whole body), and melatonin plus RF-EMR. After exposure, researchers evaluated oxidative stress parameters, testosterone level, and testicular histopathology. RF-EMR exposure induced oxidative stress, testicular tissue damage, and decreased testosterone. Melatonin treatment improved oxidative stress parameters (MDA and GSH), testis injury score, increased germinal epithelial thickness and seminiferous tubule diameter, and decreased testosterone in EMR-exposed mice, with significant differences (p < .05).
Why This Matters
The researchers aimed to evaluate whether melatonin could protect against testicular damage caused by RF-EMR from mobile phones. They noted that RF-EMR from mobile devices has undesirable effects on male reproductive organs and that melatonin has antioxidant potential to prevent such damage. The authors concluded that melatonin's antioxidant property can decrease oxidative damage induced by RF-EMR on testis tissue.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{the_protective_effect_of_melatonin_on_radiofrequency_electromagnetic_fields_of_mobile_phone_induced_testicular_damage_in_an_experimental_mouse_model_ce2602,
author = {Unknown},
title = {The protective effect of melatonin on radiofrequency electromagnetic fields of mobile phone-induced testicular damage in an experimental mouse model},
year = {2020},
doi = {10.1111/and.13834},
}