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THERMAL AND ATHERMAL EFFECTS OF MICROWAVE RADIATION ON THE ACTIVITY OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN HUMAN BLOOD

No Effects Found

M. L. BELKHODE, D. L. JOHNSON and A. M. MUC · 1974

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2.8 GHz microwaves showed no non-thermal effects on blood enzymes at extremely high power levels.

Plain English Summary

Summary written for general audiences

Researchers exposed human blood to 2.8 GHz microwave radiation at high power levels (500-1000 mW/cm²) to test effects on glucose-6-phosphate dehydrogenase. While heat from the microwaves reduced enzyme activity by up to 80%, the study found no non-thermal effects from the microwave radiation itself. This suggests microwave effects on this enzyme are purely due to heating, not electromagnetic fields.

Why This Matters

This 1974 study provides important context for understanding microwave effects on cellular function. The research specifically separated thermal effects (from heating) from potential non-thermal electromagnetic effects - a critical distinction often overlooked in EMF research. The incident power densities were 500-1000 mW/cm², with 230 ± 70 mW/cm² absorbed.

While the study found no non-thermal effects on this specific enzyme, the research design itself is noteworthy. By holding temperature fixed while varying microwave exposure, the researchers could distinguish between effects caused by heating versus electromagnetic fields themselves.

Finding

The observed average athermal effect on the relative activity was (0.4 +: 1.8)%. This is not statistically significant. Thus no athermal effect of microwave radiation on the activity of glucose-6-phosphate dehydrogenase was observed.

In their words

“The observed average athermal effect on the relative activity was (0.4 +: 1.8)%. This is not statistically significant. Thus no athermal effect of microwave radiation on the activity of glucose-6-phosphate dehydrogenase was observed.”

Figures from the Original Paper

Diagrams extracted from the original research document.

diagramPage 2 - Fig. 1. Schematic diagram of the apparatus.
graphPage 5 - Figure 3. Relative activity of human erythrocyte glucose-6-phosphate dehydrogenase as a function of temperature.
chartPage 6 - Figure 4. Relative activity of yeast glucose-6-phosphate dehydrogenase as a function of temperature: treatment with microwave radiation and without microwave radiation.
Cite This Study
M. L. BELKHODE, D. L. JOHNSON and A. M. MUC (1974). THERMAL AND ATHERMAL EFFECTS OF MICROWAVE RADIATION ON THE ACTIVITY OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN HUMAN BLOOD.
Show BibTeX
@article{thermal_and_athermal_effects_of_microwave_radiation_on_the_activity_of_glucose_6_g5877,
  author = {M. L. BELKHODE and D. L. JOHNSON and A. M. MUC},
  title = {THERMAL AND ATHERMAL EFFECTS OF MICROWAVE RADIATION ON THE ACTIVITY OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE IN HUMAN BLOOD},
  year = {1974},
  
  
}
No DOI on file for this study.

Quick Questions About This Study

The study used incident power densities between 500-1000 mW/cm², with absorbed power of 230±70 mW/cm². This corresponds to absorbed energies of 35 and 62 J/cm² for the two treatment times used.
The microwave radiation caused thermal effects (up to 80% reduction in enzyme activity from heating) but showed no statistically significant non-thermal electromagnetic effects. The observed average non-thermal effect was (0.4 ± 1.8)%, which is not statistically significant.
They maintained fixed temperatures (37°, 46.7°, and 49.7°C) during microwave exposure, allowing them to distinguish between effects caused by heating versus electromagnetic fields themselves. This controlled approach isolated non-thermal mechanisms.
The study examined glucose-6-phosphate dehydrogenase activity in human blood and yeast.
The power absorbed was 230 ± 70 mW/cm², corresponding to absorbed energies of 35 and 62 J/cm² for the two treatment times used.