Electromagnetic radiation (Wi-Fi) and epilepsy induce calcium entry and apoptosis through activation of TRPV1 channel in hippocampus and dorsal root ganglion of rats.
Ghazizadeh V, Nazıroğlu M. · 2014
View Original AbstractWi-Fi radiation activated brain calcium channels that increased cell death in epileptic rats, suggesting neurologically vulnerable people may face heightened risks.
Plain English Summary
Researchers exposed brain tissue from epileptic rats to Wi-Fi radiation for one hour. The exposure triggered harmful calcium buildup and cell death in brain regions controlling memory and pain. This suggests Wi-Fi may worsen neurological conditions by disrupting normal brain cell function.
Why This Matters
This study reveals a concerning mechanism by which Wi-Fi radiation may amplify neurological damage, particularly in vulnerable populations. The research demonstrates that 2.45 GHz radiation - the same frequency used by most home Wi-Fi routers - can activate calcium channels in brain neurons, leading to cellular stress and death. What makes this especially significant is that the effect was most pronounced in already-compromised brain tissue, suggesting people with neurological conditions like epilepsy may be at heightened risk. The researchers identified the specific pathway (TRPV1 channels) through which this damage occurs, providing crucial mechanistic evidence that Wi-Fi exposure isn't just correlated with brain effects but may actually cause them. While this was an animal study using isolated brain tissue, it adds to growing evidence that our daily Wi-Fi exposure may not be as benign as regulatory agencies assume.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 2.45 GHz Duration: 1 hour
Study Details
we tested the effects of Wi-Fi (2.45 GHz) exposure on Ca2+ influx, oxidative stress and apoptosis through TRPV1 channel in the murine dorsal root ganglion (DRG) and hippocampus of pentylentetrazol (PTZ)-induced epileptic rats.
Rats in the present study were divided into two groups as controls and PTZ. The PTZ groups were divi...
The cytosolic free Ca2+, reactive oxygen species production, apoptosis, mitochondrial membrane depol...
In conclusion, epilepsy and Wi-Fi in our experimental model is involved in Ca2+ influx and oxidative stress-induced hippocampal and DRG death through activation of TRPV1 channels, and negative modulation of this channel activity by CPZ pretreatment may account for the neuroprotective activity against oxidative stress.
Show BibTeX
@article{v_2014_electromagnetic_radiation_wifi_and_1638,
author = {Ghazizadeh V and Nazıroğlu M.},
title = {Electromagnetic radiation (Wi-Fi) and epilepsy induce calcium entry and apoptosis through activation of TRPV1 channel in hippocampus and dorsal root ganglion of rats.},
year = {2014},
doi = {10.1007/s11011-014-9549-9},
url = {https://link.springer.com/article/10.1007/s11011-014-9549-9},
}