3,138 Studies Reviewed. 77.4% Found Biological Effects. The Evidence is Clear.

Fifty-Hertz electromagnetic fields facilitate the induction of rat bone mesenchymal stromal cells to differentiate into functional neurons

Bioeffects Seen

Bai WF, Xu WC, Feng Y, Huang H, Li XP, Deng CY, Zhang MS. · 2013

View Original Abstract
Share:

Power-frequency magnetic fields at therapeutic levels can guide stem cells to become functional neurons, proving EMFs are biologically active.

Plain English Summary

Summary written for general audiences

Chinese researchers exposed stem cells from rat bone marrow to 50 Hz magnetic fields (the same frequency as power lines) for one hour daily over 12 days. The electromagnetic field exposure helped these stem cells transform into functional brain neurons that could form connections and transmit electrical signals. This suggests that power-frequency magnetic fields might have therapeutic potential for treating nervous system diseases through stem cell therapy.

Why This Matters

This study reveals a fascinating biological response to extremely low frequency magnetic fields that challenges conventional thinking about EMF effects. At 5 milliTesla, the exposure was roughly 5,000 times stronger than typical household magnetic field levels (which range from 0.5 to 4 milliGauss or 0.00005 to 0.0004 mT near appliances). What makes this research particularly significant is that it demonstrates EMFs can trigger beneficial cellular changes under controlled laboratory conditions. The reality is that electromagnetic fields are bioactive - they can influence cellular processes in both potentially harmful and beneficial ways depending on the frequency, intensity, duration, and biological context. While this specific finding explores therapeutic applications rather than health risks, it reinforces the fundamental principle that EMF exposure is not biologically neutral. The science demonstrates that our cells respond to electromagnetic signals, which is why understanding optimal exposure levels and protecting against excessive exposure from everyday sources remains crucial for public health.

Exposure Details

Magnetic Field
5 mG
Source/Device
50 Hz
Exposure Duration
60 min/day for up to 12 days

Exposure Context

This study used 5 mG for magnetic fields:

Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.

Where This Falls on the Concern Scale

Study Exposure Level in ContextA logarithmic scale showing exposure levels relative to Building Biology concern thresholds and regulatory limits.Study Exposure Level in ContextThis study: 5 mGExtreme Concern5 mGFCC Limit2,000 mGEffects observed in the Extreme Concern range (Building Biology)FCC limit is 400x higher than this exposure level

Study Details

In the present study, we explored the efficacy of EMF on the induction of rat BMSC differentiation into neurons in vitro.

First, rat BMSC were induced in a nerve cell culture environment and divided into three groups: an E...

The results indicated that EMF can facilitate BMSC differentiation into neural cells, which expresse...

Given that a noninvasive treatment of 50-Hz EMF could significantly facilitate BMSC to differentiate into functional neurons, EMF appears to be a promising clinical option for stem cell transplantation therapies to combat central nervous system diseases.

Cite This Study
Bai WF, Xu WC, Feng Y, Huang H, Li XP, Deng CY, Zhang MS. (2013). Fifty-Hertz electromagnetic fields facilitate the induction of rat bone mesenchymal stromal cells to differentiate into functional neurons Cytotherapy. 15(8):961-970, 2013.
Show BibTeX
@article{wf_2013_fiftyhertz_electromagnetic_fields_facilitate_220,
  author = {Bai WF and Xu WC and Feng Y and Huang H and Li XP and Deng CY and Zhang MS.},
  title = {Fifty-Hertz electromagnetic fields facilitate the induction of rat bone mesenchymal stromal cells to differentiate into functional neurons},
  year = {2013},
  
  url = {https://www.sciencedirect.com/science/article/abs/pii/S1465324913004489},
}

Quick Questions About This Study

Chinese researchers exposed stem cells from rat bone marrow to 50 Hz magnetic fields (the same frequency as power lines) for one hour daily over 12 days. The electromagnetic field exposure helped these stem cells transform into functional brain neurons that could form connections and transmit electrical signals. This suggests that power-frequency magnetic fields might have therapeutic potential for treating nervous system diseases through stem cell therapy.