Wi-Fi (2.4 GHz) affects anti-oxidant capacity, DNA repair genes expression and, apoptosis in pregnant mouse placenta
Authors not listed · 2020
Pregnant mice exposed to Wi-Fi signal (2.4 GHz) showed increased lipid peroxidation, SOD activity, apoptosis, and CDKN1A and GADD45a overexpression in placenta.
Plain English Summary
Pregnant mice were exposed to Wi-Fi signal (2.4 GHz) for 2 and 4 hours. Placenta tissues were examined for MDA and SOD levels, and gene expression of SOD, CDKNA1, GADD45a, Bax, and Bcl-2 was measured by real-time PCR, while apoptosis was assessed using TUNEL assay. MDA and SOD levels significantly increased in exposed groups (P-value<0.05), and SOD mRNA expression also significantly increased. CDKN1A and GADD45a gene expression increased in exposed groups (P-value<0.05), and apoptosis increased as shown by quantitative PCR and TUNEL assay (P-value<0.05).
Why This Matters
The researchers used one-way ANOVA with Prism version 6.0 software to analyze the results. The authors concluded that Wi-Fi signals increase lipid peroxidation, SOD activity, apoptosis, and CDKN1A and GADD45a overexpression in mouse placenta tissue. They noted that further experimental studies are warranted to investigate other genes and aspects of pregnancy to determine the role of Wi-Fi radiation on fertility and pregnancy.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{wi_fi_24_ghz_affects_anti_oxidant_capacity_dna_repair_genes_expression_and_apoptosis_in_pregnant_mouse_placenta_ce2630,
author = {Unknown},
title = {Wi-Fi (2.4 GHz) affects anti-oxidant capacity, DNA repair genes expression and, apoptosis in pregnant mouse placenta},
year = {2020},
doi = {10.22038/ijbms.2020.40184.9512},
}