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The effects of extremely low frequency magnetic fields on mutation induction in mice

No Effects Found

Wilson JW et al · 2015

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Blood mutation frequency did not differ from controls, while sperm showed a marginally significant, non-dose-dependent increase.

Plain English Summary

Summary written for general audiences

Researchers exposed seven-week-old male mice to 10, 100, or 300 μT, 50 Hz magnetic fields for 2 or 15 hours. They measured mutation frequency at the ESTR Ms6-hm locus in sperm and blood using single-molecule PCR. Blood mutation frequency did not differ from sham controls, and sperm showed a marginally significant, non-dose-dependent increase. Acute X-ray exposure produced significant mutation increases in both sperm and blood.

Why This Matters

The authors concluded that the in vivo mutagenic effects of ELF magnetic fields are likely minor or negligible within the tested dose range. They stated that the results suggest minor if not negligible mutagenic effects of ELF magnetic fields at the doses analyzed.

Exposure Information

A logarithmic frequency spectrum from 10 Hz to 100 GHz showing where this study's 50 Hz exposure sits relative to common EMF sources.Where This Frequency Sits on the EMF SpectrumELFVLFLF / MFHF / VHFUHFSHFmm10 Hz100 GHzThis study: 50 HzCell phones~1 GHzWiFi2.4 GHz5G mm28 GHzLogarithmic scale

Specific exposure levels were not quantified in this study.

Cite This Study
Wilson JW et al (2015). The effects of extremely low frequency magnetic fields on mutation induction in mice.
Show BibTeX
@article{wilson_jw_et_al_march_2015_the_effects_of_extremely_low_frequency_magnetic_fields_on_mutation_induction_in_mice_mutat_res_2015_mar77322_6_doi_101016jmrfmmm201501014_ce2043,
  author = {Wilson JW et al},
  title = {The effects of extremely low frequency magnetic fields on mutation induction in mice},
  year = {2015},
  doi = {10.1016/j.mrfmmm.2015.01.014},
  
}

Quick Questions About This Study

Mice were exposed to 10, 100, or 300 μT, 50 Hz magnetic fields for 2 or 15 hours.
Mutation frequency at the ESTR Ms6-hm locus was measured in sperm and blood using single-molecule PCR.
Blood mutation frequency did not significantly differ from sham-treated controls.
Sperm showed a marginally significant increase in mutation frequency that was not dose-dependent.