Chemoprotective action of lotus seedpod procyanidins on oxidative stress in mice induced by extremely low-frequency electromagnetic field exposure.
Luo X, Chen M, Duan Y, Duan W, Zhang H, He Y, Yin C, Sun G, Sun X · 2016
View Original AbstractLotus seedpod procyanidins reduced oxidative stress markers in mice exposed to extremely low-frequency electromagnetic fields.
Plain English Summary
Researchers tested whether lotus seedpod procyanidins (LSPCs) could protect mice against oxidative stress caused by extremely low-frequency electromagnetic field (ELF-EMF) exposure. Mice were exposed to ELF-EMF at 8 mT, 4 hours per day for 28 consecutive days, and blood and cerebral cortex were analyzed for antioxidant indices. LSPCs treatment augmented SOD, CAT, GSH-Px, GR and GST activity and significantly lowered MDA levels.
Why This Matters
Sixty male ICR mice were randomly divided into five equal groups for the experiment. A control group received neither LSPCs nor ELF-EMF exposure, while one group received ELF-EMF exposure with no LSPCs, and three groups received ELF-EMF exposure plus LSPCs at doses of 60, 90, or 120 mg per kg body weight. The researchers suggested the protective effect may be related to LSPCs' ability to scavenge free radicals and stimulate antioxidant enzyme activity.
Exposure Details
- Magnetic Field
- 8 mT
- Exposure Duration
- 28 days (4 h/day)
Exposure Context
This study used 8 mT for magnetic fields:
- 400Kx above the Building Biology guideline of 0.2 mG
- 80Kx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
In this study, lotus seedpod procyanidins (LSPCs) were evaluated for their protective effects on ELF-EMF induced oxidative stress injury in mice.
Sixty male ICR mice were used for the experiment. The mice were randomly divided into five equal gro...
LSPCs administration at different doses significantly inhibited oxidative stress damage of mice indu...
Show BibTeX
@article{x_2016_chemoprotective_action_of_lotus_410,
author = {Luo X and Chen M and Duan Y and Duan W and Zhang H and He Y and Yin C and Sun G and Sun X},
title = {Chemoprotective action of lotus seedpod procyanidins on oxidative stress in mice induced by extremely low-frequency electromagnetic field exposure.},
year = {2016},
url = {https://www.sciencedirect.com/science/article/abs/pii/S0753332216305807},
}