Effects of extremely low frequency magnetic field on oxidative balance in brain of rats.
Ciejka E, Kleniewska P, Skibska B, Goraca A. · 2011
View Original AbstractIn rats, a 30-minute daily magnetic field exposure increased lipid peroxidation in the brain, while 60-minute daily exposure triggered an apparent adaptive response instead.
Plain English Summary
The study aimed to assess the effect of extremely low frequency magnetic field parameters on reactive oxygen species generation in brain tissue of experimental animals depending on the time of exposure. Exposure at 30 min/day for 10 days caused a significant increase in lipid peroxidation and an insignificant increase in hydrogen peroxide and free sulphydryl groups. Exposure at 60 min/day caused a significant increase in free sulphydryl groups and protein concentration, which the researchers described as indicating an adaptive mechanism.
Why This Matters
The animals were divided into 3 groups: a control group, a group exposed for 30 min/day for 10 days, and a group exposed for 60 min/day for 10 days, with all other field parameters held the same. The oxidative stress markers measured included thiobarbituric acid reactive substances, hydrogen peroxide, total free sulphydryl groups, and protein in brain homogenates. The researchers concluded that the effect of ELF-MF irradiation on oxidative stress parameters depends on the time of animal exposure to magnetic field.
Exposure Details
- Magnetic Field
- 7 mT
- Source/Device
- 40 Hz
- Exposure Duration
- 30 min/day, 10 days
Exposure Context
This study used 7 mT for magnetic fields:
- 350Kx above the Building Biology guideline of 0.2 mG
- 70Kx above the BioInitiative Report recommendation of 1 mG
Building Biology guidelines are practitioner-based limits from real-world assessments. BioInitiative Report recommendations are based on peer-reviewed science. Check Your Exposure to compare your own measurements.
Where This Falls on the Concern Scale
Study Details
The aim of the study is to assess the effect of ELF-MF parameters most frequently used in magnetotherapy on reactive oxygen species generation (ROS) in brain tissue of experimental animals depending on the time of exposure to this field.
The research material included adult male Sprague-Dawley rats, aged 3-4 months. The animals were div...
ELF-MF parameters of 7 mT, 40 Hz, 30 min/day for 10 days caused a significant increase in lipid pero...
The study has shown that ELF-MF applied for 30 min/day for 10 days can affect free radical generation in the brain. Prolongation of the exposure to ELF-MF (60/min/day) caused adaptation to this field. The effect of ELF-MF irradiation on oxidative stress parameters depends on the time of animal exposure to magnetic field.
Show BibTeX
@article{e_2011_effects_of_extremely_low_231,
author = {Ciejka E and Kleniewska P and Skibska B and Goraca A. },
title = {Effects of extremely low frequency magnetic field on oxidative balance in brain of rats.},
year = {2011},
url = {https://www.researchgate.net/profile/Anna-Goraca/publication/221814778_Effect_of_extremely_low_frequency_magnetic_field_on_oxidative_balance_in_brain_of_rats/links/542909a10cf26120b7b57a8b/Effect-of-extremely-low-frequency-magnetic-field-on-oxidative-balance-in-brain-of-rats.pdf},
}