p25/CDK5 is partially involved in neuronal injury induced by radiofrequency electromagnetic field exposure
Zhang Y, She F, Li L, Chen C, Xu S, Luo X, Li M, He M, Yu Z. · 2013
View Original AbstractJust 10 minutes of WiFi-frequency radiation triggered neuronal damage and cell death in developing brain cells.
Plain English Summary
Researchers exposed newborn rat brain cells to 2.45 GHz radiofrequency radiation (the same frequency used in WiFi and microwave ovens) for just 10 minutes and found significant neuronal damage. The radiation triggered a harmful cellular pathway that led to decreased cell survival, increased cell death, and abnormal protein changes associated with neurodegeneration. This suggests that even brief RF exposure can activate damaging processes in developing brain cells.
Why This Matters
This study adds to mounting evidence that radiofrequency radiation can directly damage brain cells through specific molecular pathways. What's particularly concerning is that researchers observed these effects after just 10 minutes of exposure to 2.45 GHz radiation - the same frequency emitted by WiFi routers, smartphones, and microwave ovens. The fact that the damage occurred in developing neurons makes this especially relevant for children, whose brains are still forming. The researchers identified the specific cellular mechanism (the p25/CDK5 pathway) involved in the damage, which strengthens the biological plausibility of RF-EMF health effects. While this was a laboratory study using isolated cells rather than whole animals, it demonstrates that RF radiation can trigger the same type of protein abnormalities seen in neurodegenerative diseases. The science demonstrates that our everyday wireless devices operate at frequencies capable of disrupting normal brain cell function.
Exposure Information
Specific exposure levels were not quantified in this study. The study examined exposure from: 2.45 GHz RF-EMF Duration: 10 min
Study Details
The aim of the present work was to investigate whether the cyclin-dependent kinase 5 (CDK5) pathway is involved in neuronal injury induced by RF-EMF exposure.
Newborn Sprague-Dawley rats’ primary cultured cortical neurons were exposed to pulsed 2.45 GHz RF-EM...
The cellular viability of neurons was significantly decreased (p < 0.01, Partial Eta Squared [ηp2]: ...
These results suggest that abnormal activity of p25/CDK5 is partially involved in primary cultured cortical neuron injury induced by RF-EMF exposure.
Show BibTeX
@article{y_2013_p25cdk5_is_partially_involved_1550,
author = {Zhang Y and She F and Li L and Chen C and Xu S and Luo X and Li M and He M and Yu Z.},
title = {p25/CDK5 is partially involved in neuronal injury induced by radiofrequency electromagnetic field exposure},
year = {2013},
doi = {10.3109/09553002.2013.817699},
url = {https://www.tandfonline.com/doi/abs/10.3109/09553002.2013.817699},
}