Effects of 5G mobile phone network electromagnetic field exposure on testicular endoplasmic reticulum stress and the protective role of coenzyme Q10
Yilmaz H, Tümkaya L, Mercantepe T, Yılmaz A, Gül F, Suzan ZT · 2025
Rats exposed to 5.9 GHz EMF developed testicular histopathological damage and oxidative stress that were reversed by coenzyme Q10 treatment.
Plain English Summary
Researchers exposed male Sprague-Dawley rats to 5.9 GHz electromagnetic fields for two hours daily over 30 days. The EMF exposure caused histopathological damage including edema, vascular congestion, inflammation, and loss of sperm cells. EMF exposure also increased oxidative stress markers and endoplasmic reticulum stress proteins in testicular tissue. Coenzyme Q10 treatment reversed both the histopathological and biochemical changes caused by EMF exposure.
Why This Matters
The study used three groups of eight rats each, with a control group receiving only saline. Coenzyme Q10 was administered at 10 mg/kg daily, dissolved in corn oil at 2 mg/kg. The researchers concluded that due to its antioxidant properties and ability to suppress oxidative stress and apoptosis, CoQ10 may be a promising candidate against 5 G EMF-induced testicular ER damage.
Exposure Information
Specific exposure levels were not quantified in this study.
Show BibTeX
@article{yilmaz_h_tmkaya_l_mercantepe_t_ylmaz_a_gl_f_suzan_zt_ce2657,
author = {Yilmaz H and Tümkaya L and Mercantepe T and Yılmaz A and Gül F and Suzan ZT},
title = {Effects of 5G mobile phone network electromagnetic field exposure on testicular endoplasmic reticulum stress and the protective role of coenzyme Q10},
year = {2025},
doi = {10.1016/j.arcmed.2024.103157},
}