8,700 Studies Reviewed. 87.0% Found Biological Effects. The Evidence is Clear.
Shield Your Body
Whole Body / General208 citations

Effects of exposure to extremely low frequency electromagnetic fields on hippocampal long-term potentiation in hippocampal CA1 region

Bioeffects Seen

Zheng Y, Cheng J, Dong L, Ma X, Kong Q · 2019

Share:

Insufficient information to determine key finding.

Plain English Summary

Summary written for general audiences

Insufficient information provided. Based on the title alone, this study examined the effects of extremely low frequency (ELF) electromagnetic field exposure on hippocampal long-term potentiation in the CA1 region. However, no abstract was provided to verify the actual findings or confirm the organism used (the record indicates 'microorganism' which conflicts with the hippocampal CA1 focus in the title).

Why This Matters

Long-term potentiation (LTP) in hippocampal CA1 is a well-established model for studying synaptic plasticity and memory formation. The organism designation as 'microorganism' appears inconsistent with hippocampal tissue studies and requires clarification.

Exposure Information

Specific exposure levels were not quantified in this study.

Cite This Study
Zheng Y, Cheng J, Dong L, Ma X, Kong Q (2019). Effects of exposure to extremely low frequency electromagnetic fields on hippocampal long-term potentiation in hippocampal CA1 region.
Show BibTeX
@article{zheng_y_cheng_j_dong_l_ma_x_kong_q_ce4619,
  author = {Zheng Y and Cheng J and Dong L and Ma X and Kong Q},
  title = {Effects of exposure to extremely low frequency electromagnetic fields on hippocampal long-term potentiation in hippocampal CA1 region},
  year = {2019},
  doi = {10.1038/s42003-020-01127-5},
  
}
DOI: 10.1038/s42003-020-01127-5

Quick Questions About This Study

The large number of participating laboratories was essential to test whether the calibration methods would work consistently across different instruments, researchers, and laboratory conditions worldwide, ensuring the protocols would be reliable for widespread scientific use.
Silica microspheres produced highly precise calibration with 95.5% of measurements within 1.2-fold accuracy, were easy to quality control, could assess instrument linear range, and allowed combination with fluorescence measurements for comprehensive calibration.
The fluorescence measurements between plate readers and flow cytometry showed only a 1.07-fold mean difference, demonstrating that properly calibrated instruments can produce nearly identical results across different measurement technologies.
MEFL (Molecules of Equivalent Fluorescein) units enable direct comparison and data fusion between different measurement methods like plate readers and flow cytometry, allowing researchers to combine and compare data from multiple laboratory techniques.
Without standardized calibration, optical density measurements cannot be compared between different instruments or laboratories, making it impossible to reproduce results or combine data from multiple research groups studying the same biological processes.